Ask the Doctor
Questions about kidney disease? Risk factors? Signs and symptoms? Are you concerned about yourself, a friend or family member? Ask Dr. Spry.
Cardiovascular disease means having problems with your heart and the blood vessels throughout your body, including brain, lungs and legs. Heart and blood vessel disease is common in people with chronic kidney disease (CKD). Over time, the blood vessels that bring blood to the heart and brain can become blocked from a buildup of cells, fat and cholesterol. This reduces blood flow to the heart and brain and can cause heart attacks and strokes.
Yes. Some of the most common ones are:
Yes. Dialysis patients are much more likely than the general population to develop heart and blood vessel disease. This increased risk is related to kidney disease and other health problems like diabetes and high blood pressure. For this reason, it’s very important for dialysis patients to follow the steps to help prevent heart and blood vessel problems (see next section). If heart and blood vessel problems occur, patients need to follow their treatment plan carefully to avoid complications like heart attacks and strokes.
Yes. Take steps to control health problems that can lead to heart and blood vessel disease, especially diabetes and high blood pressure. Follow a healthy lifestyle-eat the right foods, exercise regularly and stop smoking.
Here are some steps that can help prevent heart and blood vessel disease. Speak to your doctor about them. The doctor and other members of your health care team will work with you to develop a care plan that meets your needs.
Check your blood sugar as often as your doctor tells you to. Follow your treatment plan of medications, diet and exercise.
Follow your treatment plan carefully to control high blood pressure. The blood pressure pills usually preferred for people with CKD are called angiotensin converting enzyme (ACE) inhibitors or angiotensin receptor blockers (ARBs). They help to protect your heart. Be sure to follow your fluid and sodium (salt) limits to keep fluid from building up in your body and increasing your blood pressure. Ask your health care team about other steps to help prevent fluid buildup.
The target blood pressure for dialysis patients before a dialysis treatment is less than 140/90. The target blood pressure after a dialysis treatment is less than 130/80. Ask your doctor or nurse if your blood pressure readings are on target. If you check your own blood pressure at home, keep a record of your daily blood pressures and show this to your doctor at each visit. If your blood pressure readings are not on target, ask your doctor what can be done to improve them.
High blood levels of fats like cholesterol increase your chance of developing heart and blood vessel problems. You will have blood tests to check for total cholesterol and other fats in your blood. If your levels are too high, you may need to follow a low-fat diet and exercise more. Some patients may also need to take pills (such as a Statin) to help lower cholesterol.
Your diet should have the right amount of protein and calories to keep you at a healthy weight. Your doctor and dietitian may also ask you to:
If you are on a protein or potassium modified diet, speak to your doctor and dietitian before making any changes in your diet.
Be sure to ask your doctor about an exercise program that is right for you. Regular exercise helps you:
CKD patients often develop anemia-a low red blood cell count. This makes you feel tired and can lead to a heart problem called left ventricular hypertrophy. This is a thickening of the muscle on the left side of the heart. Anemia can be treated with a hormone called erythropoietin (EPO) and extra iron. Correcting anemia helps to keep your heart healthy.
Keep important minerals—calcium and phosphorus—in balance.
These important minerals get out of balance when you have CKD. As a result, bones lose calcium and weaken over time. Some calcium may end up in parts of your body where it does not belong, like your heart and blood vessels. This makes your blood vessels get stiffer and narrower. When this happens, you are more likely to have a heart attack or stroke. You may need to:
Your doctor may ask you to take aspirin to help prevent heart attacks. Sometimes aspirin can cause bleeding problems. Ask your doctor what signs and symptoms you should look for to check for bleeding problems caused by aspirin.
Homocysteine is an amino acid that is made in your body. High levels of homocysteine in your blood are associated with an increased chance of having heart and blood vessel problems. Getting enough folic acid, vitamin B6 and vitamin B12 helps keep homocysteine levels in the normal range. Ask your doctor to give you the name of a vitamin that contains the right amounts of folic acid, vitamin B6 and vitamin B12 for people with kidney disease.
Stop smoking if you are a smoker
If you are a smoker, ask your doctor about a program to help you quit.
Smoking makes you more likely to develop heart and blood vessel disease.
At times, dialysis patients may feel depressed, angry or upset. These feelings can make it harder for you to follow your treatment plan, improve your health and return to your normal routine. They may also increase your chance of developing heart disease or of making it worse. It’s important to get treatment if you have these feelings. Talk to your dialysis social worker or your doctor to find out if counseling and/or medications may be helpful.
Yes. To check how well your heart is working, you should have:
If these tests show any problem, you may also need to have:
Your treatment will depend on the exact type of heart and blood vessel disease you have. See the chart to find out about some of the treatments used for the most common types of heart and blood vessel disease. If you have a different type, your doctor will speak to you about the treatment you need.
You should speak to your doctor and other members of your health care team. You may also want to check the following information from the National Kidney Foundation (NKF):
Booklets
Heart Health on Dialysis: How Lipids Can Affect Your Heart (English: Order # 11-50-2107 and Spanish: Order # 11-50-2191)
Nutrition and Hemodialysis (Order # 11-50-0136)
Nutrition and Peritoneal Dialysis (Order # 11-50-0140)
Staying Fit With Chronic Kidney Disease (Order # 11-10-0502)
Coping Effectively: A Guide for Patients and Their Families (Order # 11-10-0503)
High Blood Pressure and Chronic Kidney Disease (Stages 1-4) (English: Order # 11-10-0212 and Spanish: Order # 11-10-1204)
What You Need to Know About Anemia and Chronic Kidney Disease (English: Order # 11-10-0281 and Spanish: Order # 11-10-0286)
Lab Log (for keeping track of lab values) (Order # 11-50-0130)
Fact Sheets (available at www.kidney.org/kls)
Phosphorus and Your CKD Diet
Keep Sodium Under Control: How to Spice Up Your Cooking
Cholesterol and Chronic Kidney Disease
Carbohydrate Counting in Chronic Kidney Disease
NKF Family Focus – quarterly newspaper for dialysis patients and their families and friends. Ask for a copy at your dialysis center or call the NKF at 800.622.9010
Treatments for Heart Disease
| Type of Heart Problem | Description | Common Symptoms or Findings | Potential Treatments |
| Coronary Artery Disease | One or more of the arteries that supplies blood to your heart is narrow or clogged. | Chest pain (angina) or shortness of breath, especially on exertion. History of heart attack. Abnormal ECG, Abnormal heart rhythm. Low blood pressure during hemodialysis treatments. |
A. Medications your doctor may prescribe: · Aspirin to reduce blood clotting & risk of heart attack (check with your doctor) · Beta blockers to slow heart beat & reduce angina (chest pain) · Nitrates to dilate blood vessels & reduce angina · Lipid-lowering drugs B. Angioplasty: A procedure in which a catheter (tube) with an inflatable balloon is used to widen a narrowed artery. C. Coronary bypass: A procedure in which a vein, usually from your leg, is used to bypass the clogged or narrow area in the artery. |
| Left Ventricular Hypertrophy | Thickening of the muscle of the left side of the heart, which prevents the heart from working as well. | Usually no symptoms. Abnormal ECG. |
· Controlling blood pressure (see “Keep high blood pressure controlled” for goals of high blood pressure treatment) · Treating anemia with medications (EPO & iron). |
| Heart Failure | May occur due to coronary artery disease or left ventricular hypertrophy. Causes reduced output of blood from the heart and buildup of fluid in the lungs and legs. |
Shortness of breath, especially with exertion or when lying flat. Leg swelling, especially when standing. Low blood pressure during hemodialysis treatments. |
A. Medications: · ACE inhibitors to dilate blood vessels and reduce strain on the heart. · Beta blockers to reduce strain on the heart. · Digitalis to make the heart beat stronger. B. Stricter sodium (salt) and fluid restrictions: To help reduce fluid accumulation. C. Adjusting your target weight after dialysis (dry weight). |
Abbreviations: ACE=angiotensin converting enzyme; ECG=electrocardiogram; EPO=erythropoietin.
NKF Kidney Learning System (KLS) Web Site at www.kidney.org/kls
NKF Patient and Family Council
If you would like more information, please contact us.
©2013 National Kidney Foundation. All rights reserved. This material does not constitute medical advice. It is intended for informational purposes only. No one associated with the National Kidney Foundation will answer medical questions via e-mail. Please consult a physician for specific treatment recommendations.