Diabetes and Kidney Failure: A New Tool to Break the Cycle

New York, NY
April 12, 2007

The National Kidney Foundation presented the first comprehensive guidelines on chronic kidney disease (CKD) and diabetes as part of its Kidney Disease Outcomes Quality Initiative TM (KDOQI TM, www.kdoqi.org) session at the 2007 Spring Clinical Meetings, held here today. The guidelines recommend annual testing of diabetic patients for kidney disease, while highlighting the need for microalbuminuria detection. Screening should include measurements of urinary albumin-to-creatinine ratio (ACR) in a spot urine sample and measurement of serum creatinine to estimate the glomerular filtration rate (GFR).

“Physicians know that diabetes has become a worldwide pandemic and that it attacks the heart and vascular system -- including the kidneys. Diabetes now is the leading cause of kidney failure in the developed world. The KDOQI TMDiabetes and CKD Clinical Practice Guidelines offer the latest information on diagnosis, staging, and treatment of diabetic kidney disease or DKD, a new term preferred to the traditional label of diabetic nephropathy,” says KDOQI TM work group co-chair Dr. Katherine Tuttle, Medical and Scientific Director of Research at Providence Medical Research Center in Spokane, Washington.

An estimated 21 million people in the U.S. have diabetes and over half of those people have kidney damage or disease. The incidence of diabetes is expected to double between 2000 and 2030.

“Practitioners from around the globe who manage diabetes and CKD patients will read these guidelines not only for information but for insight on the diabetes epidemic they are facing,” says NKF president Dr. Allan Collins.

According to the guidelines, all patients with diabetes should be screened for DKD because treatments that slow or prevent the disease and its complications are available. These treatments include:

  • Intensive glycemic control
  • Antihypertensive therapies
  • Cholesterol lowering
  • Dietary protein restriction.

“These Guidelines place renewed emphasis on healthy behaviors, including diet, exercise, smoking cessation, self-monitoring of blood glucose and blood pressure and adherence to medicines that prevent or treat kidney disease and its complications," continues Dr. Tuttle.

When it comes to nutrition, patients with diabetes and CKD should:

  • Consume enough protein, but avoid overindulgence.
  • Choose vegetable or soy protein sources.
  • Follow United States Department of Agriculture’s recommended daily allowance of protein as a useful, healthy guide.
  • Strive for a normal body mass index (BMI). BMI is calculated from your height and weight. BMI is an objective indicator if a person is overweight, underweight or at a healthy weight.

Guideline Work Group
The NKF- KDOQI TMClinical Practice Guidelines for Diabetes and CKD are the product of three years of reviewing evidence published in peer-reviewed medical journals and the dedication of 16 volunteer experts in nephrology, endocrinology, epidemiology, nutrition, cardiology, nursing, internal medicine and pharmacology. As with all KDOQI TM Guidelines, the document was widely distributed for public/ peer review prior to finalizing. The National Kidney Foundation gratefully acknowledges the support of Amgen and Keryx, which made development of these guidelines possible.

About the National Kidney Foundation
The National Kidney Foundation is dedicated to preventing kidney and urinary tract diseases, improving the health and well being of individuals and families affected by these diseases, influencing public policy in support of the kidney community and increasing the availability of all organs for transplantation.

To order the guideline, please call 800-622-9010, 212-889-2210 or visit www.kidney.org.