NKF K/DOQI Guidelines

NKF K/DOQI GUIDELINES

Clinical Practice Guidelines and Clinical Practice Recommendations
2006 Updates
Hemodialysis Adequacy
Peritoneal Dialysis Adequacy
Vascular Access

I. CLINICAL PRACTICE GUIDELINES FOR HEMODIALYSIS ADEQUACY

Tables

Table 1	Validated GFR-Estimating Equations
Table 2	Causes of Unusually Low or High Endogenous Creatinine Generation
Table 3	Causes of Unusually Low or High Kidney Tubular Creatinine Secretion
Table 4	Methods for Calculating eKt/V
Table 4A	Preferred Measures of the Delivered Dose (in Order of Preference)
Table 5	Recommended Predialysis Blood-Drawing Procedure
Table 6	Slow-Blood-Flow Method for Obtaining the Postdialysis Sample
Table 7	Stop-Dialysate-Flow Method of Obtaining the Postdialysis Sample
Table 8	Effect of HD Dose on Mortality
Table 9	Fraction of Treatments With an spKt/V Greater Than 1.2 When Targeting 1.2 to 1.4 per Dialysis
Table 10	Effect of Residual Kidney Function on Mortality
Table 11	Complications That May Prompt Initiation of Kidney Replacement Therapy
Table 12	Effect of High Flux Dialysis on Mortality, Cardiovascular Mortality and β2 Microglobulin (β2M)
Table 13	Minimum spKt/V Values Corresponding to a stdKt/V of Approximately 2.0 per Week
Table 14	Effect of Dialyzer Reuse on Mortality
Table 15	Efforts to Protect RKF
Table 16	Potential Insults to RKF
Table 17	Effect of Pharmacologic Interventions on Loss of Residual Kidney Function
Table 18	Values for k at Different Dialysis Frequencies and BUN Targets
Table 19	Minimum spKt/V Required to Achieve a stdKt/V of 2.0 per Week

Figures

Figure 1.	Impact of Ultrafiltration on Delivered Dose of HD Measured By Using spKt/V and URR
Figure 2.	eKt/V as a Function of Dialysis Treatment Time
Figure 3.	Components of Postdialysis Urea (BUN) Rebound
Figure 4.	Stop-dialysate Method for Postdialysis Blood Sampling
Figure 5.	Illustration of the “Lag Phenomenon”
Figure 6.	Effect of Residual Native Kidney Clearance (Kr)