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NKF K/DOQI GUIDELINES Executive Summaries | Anemia | Hemodialysis | Peritoneal Dialysis |
K/DOQI Clinical Practice Guidelines for Bone Metabolism and Disease in Chronic Kidney Disease
REFERENCES
1. Collins AJ, Roberts TL, St Peter WL, Chen SC, Ebben J, Constantini E: United States Renal Data System assessment of the impact of the National Kidney Foundation-Dialysis Outcomes Quality Initiative guidelines. Am J Kidney Dis 39:784-795, 2002
2. Eknoyan G, Agodoa L: On improving outcomes and quality of dialysis care, and more. Am J Kidney Dis 39:889-891, 2002
3. K/DOQI clinical practice guidelines for chronic kidney disease: Evaluation, classification, and stratification. Kidney Disease Outcome Quality Initiative. Am J Kidney Dis 39:S1-S246, 2002 (suppl 1)
4. Arnaud CD: Hyperparathyroidism and renal failure. Kidney Int 4:89-95, 1973
5. Bricker NS, Slatopolsky E, Reiss E, Avioli LV: Calcium, phosphorus, and bone in renal disease and transplantation. Arch Intern Med 123:543-553, 1969
6. Coburn JW, Elangovan L, Goodman WG, Frazao JM: Calcium-sensing receptor and calcimimetic agents. Kidney Int Suppl 73:S52-S58, 1999
7. De Marchi S, Cecchin E, Villalta D, Sepiacci G, Santini G, Bartoli E: Relief of pruritus and decreases in plasma histamine concentrations during erythropoietin therapy in patients with uremia. N Engl J Med 326:969-974, 1992
8. Fukagawa M: Cell biology of parathyroid hyperplasia in uremia. Am J Med Sci 317:377-382, 1999
9. Llach F: Calcific uremic arteriolopathy (calciphylaxis): An evolving entity? Am J Kidney Dis 32:514-518, 1998
10. Llach F, Massry SG: On the mechanism of secondary hyperparathyroidism in moderate renal insufficiency. J Clin Endocrinol Metab 61:601-606, 1985
11. Martin KJ, Gonzalez EA, Gellens M, Hamm LL, Abboud H, Lindberg J: 19-Nor-1-alpha-25-dihydroxyvitamin D2 (Paricalcitol) safely and effectively reduces the levels of intact parathyroid hormone in patients on hemodialysis. J Am Soc Nephrol 9:1427-1432, 1998
12. Massry SG, Coburn JW, Lee DB, Jowsey J, Kleeman CR: Skeletal resistance to parathyroid hormone in renal failure. Studies in 105 human subjects. Ann Intern Med 78:357-364, 1973
13. Proudfoot D, Shanahan CM, Weissberg PL: Vascular calcification: New insights into an old problem. J Pathol 185:1-3, 1998
14. Sherrard DJ, Hercz G, Pei Y, Maloney NA, Greenwood C, Manuel A, Saiphoo C, Fenton SS, Segre GV: The spectrum of bone disease in end-stage renal failureAn evolving disorder. Kidney Int 43:436-442, 1993
15. Slatopolsky E, Weerts C, Thielan J, Horst R, Harter H, Martin KJ: Marked suppression of secondary hyperparathyroidism by intravenous administration of 1,25-dihydroxy-cholecalciferol in uremic patients. J Clin Invest 74:2136-2143, 1984
16. Massry SG, Coburn JW, Popovtzer MM, Shinaberger JH, Maxwell MH, Kleeman CR: Secondary hyperparathyroidism in chronic renal failure. The clinical spectrum in uremia, during hemodialysis, and after renal transplantation. Arch Intern Med 124:431-441, 1969
17. Malluche HH, Faugere MC: Effects of 1,25(OH)2D3 administration on bone in patients with renal failure. Kidney Int Suppl 29:S48-S53, 1990
18. Malluche H, Faugere MC: Renal bone disease 1990: An unmet challenge for the nephrologist. Kidney Int 38:193-211, 1990
19. Hamdy NA, Kanis JA, Beneton MN, Brown CB, Juttmann JR, Jordans JG, Josse S, Meyrier A, Lins RL, Fairey IT: Effect of alfacalcidol on natural course of renal bone disease in mild to moderate renal failure. BMJ 310:358-363, 1995
20. Goodman WG, Coburn JW: The use of 1,25-dihydroxyvitamin D3 in early renal failure. Annu Rev Med 43:227-237, 1992
21. de Caestecker MP, Bottomley M, Telfer BA, Hutchinson IV, Vose BM, Ballardie FW: Detection of abnormal peripheral blood mononuclear cell cytokine networks in human IgA nephropathy. Kidney Int 44:1298-1308, 1993
22. Feldman HI, Held PJ, Hutchinson JT, Stoiber E, Hartigan MF, Berlin JA: Hemodialysis vascular access morbidity in the United States. Kidney Int 43:1091-1096, 1993
23. Hutchison AJ, Whitehouse RW, Boulton HF, Adams JE, Mawer EB, Freemont TJ, Gokal R: Correlation of bone histology with parathyroid hormone, vitamin D3, and radiology in end-stage renal disease. Kidney Int 44:1071-1077, 1993
24. Gerakis A, Hutchison AJ, Apostolou T, Freemont AJ, Billis A: Biochemical markers for non-invasive diagnosis of hyperparathyroid bone disease and adynamic bone in patients on haemodialysis. Nephrol Dial Transplant 11:2430-2438, 1996
25. Quigg RJ, Brathwaite M, Gardner DF, Gretch DR, Ruddy S: Successful cyclophosphamide treatment of cryoglobulinemic membranoproliferative glomerulonephritis associated with hepatitis C virus infection. Am J Kidney Dis 25:798-800, 1995
26. Qi Q, Monier-Faugere MC, Geng Z, Malluche HH: Predictive value of serum parathyroid hormone levels for bone turnover in patients on chronic maintenance dialysis. Am J Kidney Dis 26:622-631, 1995
27. Block GA, Port FK: Re-evaluation of risks associated with hyperphosphatemia and hyperparathyroidism in dialysis patients: Recommendations for a change in management. Am J Kidney Dis 35:1226-1237, 2000
28. Urena P, Ferreira A, Kung VT, Morieux C, Simon P, Ang KS, Souberbielle JC, Segre GV, Drueke TB, De Vernejoul MC: Serum pyridinoline as a specific marker of collagen breakdown and bone metabolism in hemodialysis patients. J Bone Miner Res 10:932-939, 1995
29. Raggi P, Boulay A, Chasan-Taber S, Amin N, Dillon M, Burke SK, Chertow GM: Cardiac calcification in adult hemodialysis patients. A link between end-stage renal disease and cardiovascular disease? J Am Coll Cardiol 39:695-701, 2002
30. Rumberger JA, Brundage BH, Rader DJ, Kondos G: Electron beam computed tomographic coronary calcium scanning: A review and guidelines for use in asymptomatic persons. Mayo Clin Proc 74:243-252, 1999
31. Rix M, Andreassen H, Eskildsen P, Langdahl B, Olgaard K: Bone mineral density and biochemical markers of bone turnover in patients with predialysis chronic renal failure. Kidney Int 56:1084-1093, 1999
32. Ziolkowska H, Paniczyk-Tomaszewska M, Debinski A, Polowiec Z, Sawicki A, Sieniawska M: Bone biopsy results and serum bone turnover parameters in uremic children. Acta Paediatr 89:666-671, 2000
33. Wang M, Hercz G, Sherrard DJ, Maloney NA, Segre GV, Pei Y: Relationship between intact 1-84 parathyroid hormone and bone histomorphometric parameters in dialysis patients without aluminum toxicity. Am J Kidney Dis 26:836-844, 1995
34. Solal ME, Sebert JL, Boudailliez B, Marie A, Moriniere P, Gueris J, Bouillon R, Fournier A: Comparison of intact, midregion, and carboxy terminal assays of parathyroid hormone for the diagnosis of bone disease in hemodialyzed patients. J Clin Endocrinol Metab 73:516-524, 1991
35. DeVita MV, Rasenas LL, Bansal M, Gleim GW, Zabetakis PM, Gardenswartz MH, Michelis MF: Assessment of renal osteodystrophy in hemodialysis patients. Medicine (Baltimore) 71:284-290, 1992
36. Huraib S, Souqqiyeh MZ, Aswad S, al-Swailem AR: Pattern of renal osteodystrophy in haemodialysis patients in Saudi Arabia. Nephrol Dial Transplant 8:603-608, 1993
37. Eastwood JB: Quantitative bone histology in 38 patients with advanced renal failure. J Clin Pathol 35:125-134, 1982
38. Hasselblad V, Hedges LV: Meta-analysis of screening and diagnostic tests. Psychol Bull 117:167-178, 1995
39. Stehman-Breen CO, Sherrard DJ, Alem AM, Gillen DL, Heckbert SR, Wong CS, Ball A, Weiss NS: Risk factors for hip fracture among patients with end-stage renal disease. Kidney Int 58:2200-2205, 2000
40. Coco M, Rush H: Increased incidence of hip fractures in dialysis patients with low serum parathyroid hormone. Am J Kidney Dis 36:1115-1121, 2000
41. Martinez I, Saracho R, Montenegro J, Llach F: The importance of dietary calcium and phosphorous in the secondary hyperparathyroidism of patients with early renal failure. Am J Kidney Dis 29:496-502, 1997
42. Brossard JH, Lepage R, Cardinal H, Roy L, Rousseau L, Dorais C, DAmour P: Influence of glomerular filtration rate on non-(1-84) parathyroid hormone (PTH) detected by intact PTH assays. Clin Chem 46:697-703, 2000
43. Yumita S, Suzuki M, Akiba T, Akizawa T, Seino Y, Kurokawa K: Levels of serum 1,25(OH)2D in patients with pre-dialysis chronic renal failure. Tohoku J Exp Med 180:45-56, 1996
44. Fajtova VT, Sayegh MH, Hickey N, Aliabadi P, Lazarus JM, LeBoff MS: Intact parathyroid hormone levels in renal insufficiency. Calcif Tissue Int 57:329-335, 1995
45. Reichel H, Deibert B, Schmidt-Gayk H, Ritz E: Calcium metabolism in early chronic renal failure: Implications for the pathogenesis of hyperparathyroidism. Nephrol Dial Transplant 6:162-169, 1991
46. Pitts TO, Piraino BH, Mitro R, Chen TC, Segre GV, Greenberg A, Puschett JB: Hyperparathyroidism and 1,25-dihydroxyvitamin D deficiency in mild, moderate, and severe renal failure. J Clin Endocrinol Metab 67:876-881, 1988
47. Shin SK, Kim DH, Kim HS, Shin KT, Ma KA, Kim SJ, Kwak YS, Ha SK, Sherrard DJ: Renal osteodystrophy in pre-dialysis patients: Ethnic difference? Perit Dial Int 19:S402-S407, 1999 (suppl 2)
48. Malluche HH, Ritz E, Hodgson M, Kutschera J, Krause G, Seiffert U, Gati A, Lange HP: Skeletal lesions and calcium metabolism in early renal failure. Proc Eur Dial Transplant Assoc 11:443-450, 1975
49. Llach F, Massry SG, Singer FR, Kurokawa K, Kaye JH, Coburn JW: Skeletal resistance to endogenous parathyroid hormone in pateints with early renal failure. A possible cause for secondary hyperparathyroidism. J Clin Endocrinol Metab 41:339-345, 1975
50. Malluche HH, Ritz E, Lange HP, Kutschera L, Hodgson M, Seiffert U, Schoeppe W: Bone histology in incipient and advanced renal failure. Kidney Int 9:355-362, 1976
51. Sherrard DJ, Baylink DJ, Wergedal JE, Maloney NA: Quantitative histological studies on the pathogenesis of uremic bone disease. J Clin Endocrinol Metab 39:119-135, 1974
52. Fournier A, Oprisiu R, Hottelart C, Yverneau PH, Ghazali A, Atik A, Hedri H, Said S, Sechet A, Rasolombololona M, Abighanem O, Sarraj A, El Esper N, Moriniere P, Boudailliez B, Westeel PF, Achard JM, Pruna A: Renal osteodystrophy in dialysis patients: Diagnosis and treatment. Artif Organs 22:530-557, 1998
53. Coen G, Mazzaferro S, Ballanti P, Sardella D, Chicca S, Manni M, Bonucci E, Taggi F: Renal bone disease in 76 patients with varying degrees of predialysis chronic renal failure: A cross-sectional study. Nephrol Dial Transplant 11:813-819, 1996
54. Smith AJ, Faugere MC, Abreo K, Fanti P, Julian B, Malluche HH: Aluminum-related bone disease in mild and advanced renal failure: Evidence for high prevalence and morbidity and studies on etiology and diagnosis. Am J Nephrol 6:275-283, 1986
55. Hernandez D, Concepcion MT, Lorenzo V, Martinez ME, Rodriguez A, De Bonis E, Gonzalez-Posada JM, Felsenfeld AJ, Rodriguez M, Torres A: Adynamic bone disease with negative aluminum staining in predialysis patients: Prevalence and evolution after maintenance dialysis. Nephrol Dial Transplant 9:517-523, 1994
56. Pei Y, Hercz G, Greenwood C, Segre G, Manuel A, Saiphoo C, Fenton S, Sherrard D: Renal osteodystrophy in diabetic patients. Kidney Int 44:159-164, 1993
57. Andress DL, Hercz G, Kopp JB, Endres DB, Norris KC, Coburn JW, Sherrard DJ: Bone histomorphometry of renal osteodystrophy in diabetic patients. J Bone Miner Res 2:525-531, 1987
58. Carmen Sanchez M, Auxiliadora Bajo M, Selgas R, Mate A, Millan I, Eugenia Martinez M, Lopez-Barea F: Parathormone secretion in peritoneal dialysis patients with adynamic bone disease. Am J Kidney Dis 36:953-961, 2000
59. Pei Y, Hercz G, Greenwood C, Segre G, Manuel A, Saiphoo C, Fenton S, Sherrard D: Risk factors for renal osteodystrophy: A multivariant analysis. J Bone Miner Res 10:149-156, 1995
60. Hutchison AJ, Whitehouse RW, Freemont AJ, Adams JE, Mawer EB, Gokal R: Histological, radiological, and biochemical features of the adynamic bone lesion in continuous ambulatory peritoneal dialysis patients. Am J Nephrol 14:19-29, 1994
61. Malluche HH, Monier-Faugere MC: Risk of adynamic bone disease in dialyzed patients. Kidney Int Suppl 38:S62-S67, 1992
62. Hercz G, Pei Y, Greenwood C, Manuel A, Saiphoo C, Goodman WG, Segre GV, Fenton S, Sherrard DJ: Aplastic osteodystrophy without aluminum: The role of "suppressed" parathyroid function. Kidney Int 44:860-866, 1993
63. Ishimura E, Nishizawa Y, Inaba M, Matsumoto N, Emoto M, Kawagishi T, Shoji S, Okuno S, Kim M, Miki T, Morii H: Serum levels of 1,25-dihydroxyvitamin D, 24,25-dihydroxyvitamin D, and 25-hydroxyvitamin D in nondialyzed patients with chronic renal failure. Kidney Int 55:1019-1027, 1999
64. Martinez I, Saracho R, Montenegro J, Llach F: A deficit of calcitriol synthesis may not be the initial factor in the pathogenesis of secondary hyperparathyroidism. Nephrol Dial Transplant 11:22-28, 1996 (suppl 3)
65. Messa P, Vallone C, Mioni G, Geatti O, Turrin D, Passoni N, Cruciatti A: Direct in vivo assessment of parathyroid hormone-calcium relationship curve in renal patients. Kidney Int 46:1713-1720, 1994
66. Christiansen C, Christensen MS, Melsen F, Rodbro P, DeLuca HF: Mineral metabolism in chronic renal failure with special reference to serum concentrations of 1.25(OH)2D and 24.25(OH)2D. Clin Nephrol 15:18-22, 1981
67. Tessitore N, Venturi A, Adami S, Roncari C, Rugiu C, Corgnati A, Bonucci E, Maschio G: Relationship between serum vitamin D metabolites and dietary intake of phosphate in patients with early renal failure. Miner Electrolyte Metab 13:38-44, 1987
68. Malluche HH, Monier-Faugere MC: The role of bone biopsy in the management of patients with renal osteodystrophy. J Am Soc Nephrol 4:1631-1642, 1994
69. Faugere MC, Malluche HH: Stainable aluminum and not aluminum content reflects bone histology in dialyzed patients. Kidney Int 30:717-722, 1986
70. Teitelbaum SL: Renal osteodystrophy. Hum Pathol 15:306-323, 1984
71. Malluche HH, Langub MC, Monier-Faugere MC: Pathogenesis and histology of renal osteodystrophy. Osteoporos Int 7:S184-S187, 1997 (suppl 3)
72. Malluche HH, Langub MC, Monier-Faugere MC: The role of bone biopsy in clinical practice and research. Kidney Int Suppl 73:S20-S25, 1999
73. Freemont T: Histological diagnosis of renal osteodystrophy. Kidney Int Suppl 73:S26-S30, 1999
74. Couttenye MM, DHaese PC, Deng JT, Van Hoof VO, Verpooten GA, De Broe ME: High prevalence of adynamic bone disease diagnosed by biochemical markers in a wide sample of the European CAPD population. Nephrol Dial Transplant 12:2144-2150, 1997
75. Coburn JW: Mineral metabolism and renal bone disease: Effects of CAPD versus hemodialysis. Kidney Int Suppl 40:S92-S100, 1993
76. Alem AM, Sherrard DJ, Gillen DL, Weiss NS, Beresford SA, Heckbert SR, Wong C, Stehman-Breen C: Increased risk of hip fracture among patients with end-stage renal disease. Kidney Int 58:396-399, 2000
77. Atsumi K, Kushida K, Yamazaki K, Shimizu S, Ohmura A, Inoue T: Risk factors for vertebral fractures in renal osteodystrophy. Am J Kidney Dis 33:287-293, 1999
78. Parfitt AM, Drezner MK, Glorieux FH, Kanis JA, Malluche H, Meunier PJ, Ott SM, Recker RR: Bone histomorphometry: Standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee. J Bone Miner Res 2:595-610, 1987
79. Maloney NA, Ott SM, Alfrey AC, Miller NL, Coburn JW, Sherrard DJ: Histological quantitation of aluminum in iliac bone from patients with renal failure. J Lab Clin Med 99:206-216, 1982
80. Cournot-Witmer G, Zingraff J, Plachot JJ, Escaig F, Lefevre R, Boumati P, Bourdeau A, Garabedian M, Galle P, Bourdon R, Drueke T, Balsan S: Aluminum localization in bone from hemodialyzed patients: Relationship to matrix mineralization. Kidney Int 20:375-378, 1981
81. John MR, Goodman WG, Gao P, Cantor TL, Salusky IB, Juppner H: A novel immunoradiometric assay detects full-length human PTH but not amino-terminally truncated fragments: Implications for PTH measurements in renal failure. J Clin Endocrinol Metab 84:4287-4290, 1999
82. Monier-Faugere MC, Geng Z, Mawad H, Friedler RM, Gao P, Cantor TL, Malluche HH: Improved assessment of bone turnover by the PTH-(1-84)/large C-PTH fragments ratio in ESRD patients. Kidney Int 60:1460-1468, 2001
83. Slatopolsky E, Finch J, Clay P, Martin D, Sicard G, Singer G, Gao P, Cantor T, Dusso A: A novel mechanism for skeletal resistance in uremia. Kidney Int 58:753-761, 2000
84. Naveh-Many T, Rahamimov R, Livni N, Silver J: Parathyroid cell proliferation in normal and chronic renal failure rats. The effects of calcium, phosphate, and vitamin D. J Clin Invest 96:1786-1793, 1995
85. Slatopolsky E, Finch J, Denda M, Ritter C, Zhong M, Dusso A, MacDonald PN, Brown AJ: Phosphorus restriction prevents parathyroid gland growth. High phosphorus directly stimulates PTH secretion in vitro. J Clin Invest 97:2534-2540, 1996
86. Kimura K, Saika Y, Otani H, Fujii R, Mune M, Yukawa S: Factors associated with calcification of the abdominal aorta in hemodialysis patients. Kidney Int Suppl 71:S238-S241, 1999
87. Goodman WG, Goldin J, Kuizon BD, Yoon C, Gales B, Sider D, Wang Y, Chung J, Emerick A, Greaser L, Elashoff RM, Salusky IB: Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis. N Engl J Med 342:1478-1483, 2000
88. Mazhar AR, Johnson RJ, Gillen D, Stivelman JC, Ryan MJ, Davis CL, Stehman-Breen CO: Risk factors and mortality associated with calciphylaxis in end-stage renal disease. Kidney Int 60:324-332, 2001
89. Ahmed S, ONeill KD, Hood AF, Evan AP, Moe SM: Calciphylaxis is associated with hyperphosphatemia and increased osteopontin expression by vascular smooth muscle cells. Am J Kidney Dis 37:1267-1276, 2001
90. Marchais SJ, Metivier F, Guerin AP, London GM: Association of hyperphosphataemia with haemodynamic disturbances in end-stage renal disease. Nephrol Dial Transplant 14:2178-2183, 1999
91. Guerin AP, London GM, Marchais SJ, Metivier F: Arterial stiffening and vascular calcifications in end-stage renal disease. Nephrol Dial Transplant 15:1014-1021, 2000
92. Block GA, Hulbert-Shearon TE, Levin NW, Port FK: Association of serum phosphorus and calcium × phosphate product with mortality risk in chronic hemodialysis patients: A national study. Am J Kidney Dis 31:607-617, 1998
93. Lowrie EG, Lew NL: Death risk in hemodialysis patients: The predictive value of commonly measured variables and an evaluation of death rate differences between facilities. Am J Kidney Dis 15:458-482, 1990
94. Blacher J, Guerin AP, Pannier B, Marchais SJ, London GM: Arterial calcifications, arterial stiffness, and cardiovascular risk in end-stage renal disease. Hypertension 38:938-942, 2001
95. Ganesh SK, Stack AG, Levin NW, Hulbert-Shearon T, Port FK: Association of elevated serum PO(4), Ca × PO(4) product, and parathyroid hormone with cardiac mortality risk in chronic hemodialysis patients. J Am Soc Nephrol 12:2131-2138, 2001
96. Jono S, McKee MD, Murry CE, Shioi A, Nishizawa Y, Mori K, Morii H, Giachelli CM: Phosphate regulation of vascular smooth muscle cell calcification. Circ Res 87:E10-E17, 2000
97. Rostand SG, Sanders C, Kirk KA, Rutsky EA, Fraser RG: Myocardial calcification and cardiac dysfunction in chronic renal failure. Am J Med 85:651-657, 1988
98. Katz AI, Hampers CL, Merrill JP: Secondary hyperparathyroidism and renal osteodystrophy in chronic renal failure. Analysis of 195 patients, with observations on the effects of chronic dialysis, kidney transplantation and subtotal parathyroidectomy. Medicine (Baltimore) 48:333-374, 1969
99. Raggi P, Reinmuller R, Chertow GM: Cardiac calcification is prevalent and severe in ESRD patients as measured by electron beam CT scanning. J Am Soc Nephrol 75A, 2000 (abstr A0405)
100. Greene SV, Falciglia G, Rademacher R: Relationship between serum phosphorus levels and various outcome measures in adult hemodialysis patients. J Ren Nutr 8:77-82, 1998
101. Lopez-Hilker S, Dusso AS, Rapp NS, Martin KJ, Slatopolsky E: Phosphorus restriction reverses hyperparathyroidism in uremia independent of changes in calcium and calcitriol. Am J Physiol 259:F432-F437, 1990
102. Combe C, Deforges-Lasseur C, Caix J, Pommereau A, Marot D, Aparicio M: Compliance and effects of nutritional treatment on progression and metabolic disorders of chronic renal failure. Nephrol Dial Transplant 8:412-418, 1993
103. Recker RR, Saville PD: Calcium absorption in renal failure: Its relationship to blood urea nitrogen, dietary calcium intake, time on dialysis, and other variables. J Lab Clin Med 78:380-388, 1971
104. Hosking DJ, Chamberlain MJ: Calcium balance in chronic renal failure. A study using in vivo neutron activation analysis. Q J Med 42:467-479, 1973
105. Duursma SA, Visser WJ, Mees EJ, Njio L: Serum calcium, phosphate and alkaline phosphatase and morphometric bone examinations in 30 patients with renal insufficiency. Calcif Tissue Res 16:129-138, 1974
106. Better OS, Kleeman CR, Gonick HC, Varrady PD, Maxwell MH: Renal handling of calcium, magnesium and inorganic phosphate in chronic renal failure. Isr J Med Sci 3:60-79, 1967
107. Suzuki M, Hirasawa Y: Renal osteodystrophy in early chronic renal failure. Contrib Nephrol 22:28-38, 1980
108. Cochran M, Bulusu L, Horsman A, Stasiak L, Nordin BE: Hypocalcaemia and bone disease in renal failure. Nephron 10:113-140, 1973
109. Reduction of dietary protein and phosphorus in the Modification of Diet in Renal Disease Feasibility Study. The MDRD Study Group. J Am Diet Assoc 94:986-990; [quiz 991-982], 1994
110. Zeller K, Whittaker E, Sullivan L, Raskin P, Jacobson HR: Effect of restricting dietary protein on the progression of renal failure in patients with insulin-dependent diabetes mellitus. N Engl J Med 324:78-84, 1991
111. Williams PS, Stevens ME, Fass G, Irons L, Bone JM: Failure of dietary protein and phosphate restriction to retard the rate of progression of chronic renal failure: a prospective, randomized, controlled trial. Q J Med 81:837-855, 1991
112. Mahmoud MD, Bouche V, Collin P, Girault A: Effects of keto-analogues on phosphocalcic and aminoacid metabolism in dialysed patients: A crossover study. Int J Artif Organs 12:692-696, 1989
113. Klahr S, Levey AS, Beck GJ, Caggiula AW, Hunsicker L, Kusek JW, Striker G: The effects of dietary protein restriction and blood-pressure control on the progression of chronic renal disease. Modification of Diet in Renal Disease Study Group. N Engl J Med 330:877-884, 1994
114. The Modification of Diet in Renal Disease Study: Design, methods, and results from the feasibility study. Am J Kidney Dis 20:18-33, 1992
115. Malvy D, Maingourd C, Pengloan J, Bagros P, Nivet H: Effects of severe protein restriction with ketoanalogues in advanced renal failure. J Am Coll Nutr 18:481-486, 1999
116. Wingen AM, Fabian-Bach C, Schaefer F, Mehls O: Randomised multicentre study of a low-protein diet on the progression of chronic renal failure in children. European Study Group of Nutritional Treatment of Chronic Renal Failure in Childhood. Lancet 349:1117-1123, 1997
117. Herselman MG, Albertse EC, Lombard CJ, Swanepoel CR, Hough FS: Supplemented low-protein dietsAre they superior in chronic renal failure? S Afr Med J 85:361-365, 1995
118. DAmico G, Gentile MG, Fellin G, Manna G, Cofano F: Effect of dietary protein restriction on the progression of renal failure: A prospective randomized trial. Nephrol Dial Transplant 9:1590-1594, 1994
119. Dullaart RP, Beusekamp BJ, Meijer S, van Doormaal JJ, Sluiter WJ: Long-term effects of protein-restricted diet on albuminuria and renal function in IDDM patients without clinical nephropathy and hypertension. Diabetes Care 16:483-492, 1993
120. Kist-van Holthe tot Echten JE, Nauta J, Hop WC, de Jong MC, Reitsma-Bierens WC, Ploos van Amstel SL, van Acker KJ, Noordzij CM, Wolff ED: Protein restriction in chronic renal failure. Arch Dis Child 68:371-375, 1993
121. Locatelli F, Alberti D, Graziani G, Buccianti G, Redaelli B, Giangrande A: Prospective, randomised, multicentre trial of effect of protein restriction on progression of chronic renal insufficiency. Northern Italian Cooperative Study Group. Lancet 337:1299-1304, 1991
122. Forget D, Caranhac G, Quillot MJ, Besnier MO: Compliance with very low protein diet and ketoanalogues in chronic renal failure. The French Multicentric Trial IRCCA. Contrib Nephrol 81:79-86, 1990
123. Ihle BU, Becker GJ, Whitworth JA, Charlwood RA, Kincaid-Smith PS: The effect of protein restriction on the progression of renal insufficiency. N Engl J Med 321:1773-1777, 1989
124. Ando A, Orita Y, Nakata K, Fukuhara Y, Mikami H, Fujii M, Nakajima Y, Ueda N, Abe H: The effect of essential amino acid supplementation therapy on prognosis of patients with chronic renal failure estimated on the basis of the Markov process. Med J Osaka Univ 32:31-37, 1981
125. Barsotti G, Lazzeri M, Polloni A, Morelli E, Giovannetti E, Lupetti S, Cupisti A, Dani L, Giovannetti S: Effects of the impairment of renal function and of the pH of gastric secretion on the efficacy of Al(OH)3 to reduce serum inorganic phosphorus. Adv Exp Med Biol 208:493-499, 1986
126. Meisinger E, Strauch M: Controlled trial of two keto acid supplements on renal function, nutritional status, and bone metabolism in uremic patients. Kidney Int Suppl 22:S170-S173, 1987
127. Schmicker R, Vetter K, Lindenau K, Frohling PT, Kokot F: Conservative long-term treatment of chronic renal failure with keto acid and amino acid supplementation. Infusionsther Klin Ernahr 14:34-38, 1987 (suppl 5)
128. Gentile MG, Manna GM, Ferrario L, DAmico G: Preliminary experience on dietary management of chronic renal failure. Contrib Nephrol 53:102-108, 1986
129. Drueke TB: Primary and secondary uraemic hyperparathyroidism: From initial clinical observations to recent findings. Nephrol Dial Transplant 13:1384-1387, 1998
130. Popovtzer MM, Massry SG, Makoff DL, Maxwell MH, Kleeman CR: Renal handling of phosphate in patients with chronic renal failure. The role of variations in serum phosphorus and parathyroid activity. Isr J Med Sci 5:1018-1023, 1969
131. London GM, Pannier B, Marchais SJ, Guerin AP: Calcification of the aortic valve in the dialyzed patient. J Am Soc Nephrol 11:778-783, 2000
132. Milas NC, Nowalk MP, Akpele L, Castaldo L, Coyne T, Doroshenko L, Kigawa L, Korzec-Ramirez D, Scherch LK, Snetselaar L: Factors associated with adherence to the dietary protein intervention in the Modification of Diet in Renal Disease Study. J Am Diet Assoc 95:1295-1300, 1995
133. Foret M, Renversez JC, Meftahi H, Kuentz F, Milongo R, Hachache T, Vallin J, Dechelette E, Cordonnier D: How far can plasmatic levels of beta-2-microglobulin in hemodialysis be relied upon? Contrib Nephrol 62:54-59, 1988
134. Jureidini KF, Hogg RJ, van Renen MJ, Southwood TR, Henning PH, Cobiac L, Daniels L, Harris S: Evaluation of long-term aggressive dietary management of chronic renal failure in children. Pediatr Nephrol 4:1-10, 1990
135. Uauy RD, Hogg RJ, Brewer ED, Reisch JS, Cunningham C, Holliday MA: Dietary protein and growth in infants with chronic renal insufficiency: A report from the Southwest Pediatric Nephrology Study Group and the University of California, San Francisco. Pediatr Nephrol 8:45-50, 1994
136. Kopple JD, Levey AS, Greene T, Chumlea WC, Gassman JJ, Hollinger DL, Maroni BJ, Merrill D, Scherch LK, Schulman G, Wang SR, Zimmer GS: Effect of dietary protein restriction on nutritional status in the Modification of Diet in Renal Disease Study. Kidney Int 52:778-791, 1997
137. Coggins CH, Dwyer JT, Greene T, Petot G, Snetselaar LG, Van Lente F: Serum lipid changes associated with modified protein diets: Results from the feasibility phase of the Modification of Diet in Renal Disease Study. Am J Kidney Dis 23:514-523, 1994
138. Cianciaruso B, Capuano A, DAmaro E, Ferrara N, Nastasi A, Conte G, Bellizzi V, Andreucci VE: Dietary compliance to a low protein and phosphate diet in patients with chronic renal failure. Kidney Int Suppl 27:S173-S176, 1989
139. Mai ML, Emmett M, Sheikh MS, Santa Ana CA, Schiller L, Fordtran JS: Calcium acetate, an effective phosphorus binder in patients with renal failure. Kidney Int 36:690-695, 1989
140. Schiller LR, Santa Ana CA, Sheikh MS, Emmett M, Fordtran JS: Effect of the time of administration of calcium acetate on phosphorus binding. N Engl J Med 320:1110-1113, 1989
141. Slatopolsky E, Weerts C, Lopez-Hilker S, Norwood K, Zink M, Windus D, Delmez J: Calcium carbonate as a phosphate binder in patients with chronic renal failure undergoing dialysis. N Engl J Med 315:157-161, 1986
142. Balasa RW, Murray RL, Kondelis NP, Bischel MD: Phosphate-binding properties and electrolyte content of aluminum hydroxide antacids. Nephron 45:16-21, 1987
143. Emmett M, Sirmon MD, Kirkpatrick WG, Nolan CR, Schmitt GW, Cleveland MB: Calcium acetate control of serum phosphorus in hemodialysis patients. Am J Kidney Dis 17:544-550, 1991
144. Sheikh MS, Maguire JA, Emmett M, Santa Ana CA, Nicar MJ, Schiller LR, Fordtran JS: Reduction of dietary phosphorus absorption by phosphorus binders: A theoretical, in vitro, and in vivo study. J Clin Invest 83:66-73, 1989
145. Rosenbaum DP, Holmes-Farley SR, Mandeville WH, Pitruzzello M, Goldberg DI: Effect of RenaGel, a non-absorbable, cross-linked, polymeric phosphate binder, on urinary phosphorus excretion in rats. Nephrol Dial Transplant 12:961-964, 1997
146. Alfrey AC: Aluminum intoxication. N Engl J Med 310:1113-1115, 1984
147. Andreoli SP, Bergstein JM, Sherrard DJ: Aluminum intoxication from aluminum-containing phosphate binders in children with azotemia not undergoing dialysis. N Engl J Med 310:1079-1084, 1984
148. Raj DS, Charra B, Pierratos A, Work J: In search of ideal hemodialysis: is prolonged frequent dialysis the answer? Am J Kidney Dis 34:597-610, 1999
149. Mucsi I, Hercz G, Uldall R, Ouwendyk M, Francoeur R, Pierratos A: Control of serum phosphate without any phosphate binders in patients treated with nocturnal hemodialysis. Kidney Int 53:1399-1404, 1998
150. Birck R, Zimmermann E, Wassmer S, Nowack R, van der Woude FJ: Calcium ketoglutarate versus calcium acetate for treatment of hyperphosphataemia in patients on maintenance haemodialysis: A cross-over study. Nephrol Dial Transplant 14:1475-1479, 1999
151. Lerner A, Kramer M, Goldstein S, Caruana R, Epstein S, Raja R: Calcium carbonate. A better phosphate binder than aluminum hydroxide. ASAIO Trans 32:315-318, 1986
152. Bleyer AJ, Burke SK, Dillon M, Garrett B, Kant KS, Lynch D, Rahman SN, Schoenfeld P, Teitelbaum I, Zeig S, Slatopolsky E: A comparison of the calcium-free phosphate binder sevelamer hydrochloride with calcium acetate in the treatment of hyperphosphatemia in hemodialysis patients. Am J Kidney Dis 33:694-701, 1999
153. Janssen MJ, van der Kuy A, ter Wee PM, van Boven WP: Aluminum hydroxide, calcium carbonate and calcium acetate in chronic intermittent hemodialysis patients. Clin Nephrol 45:111-119, 1996
154. Pflanz S, Henderson IS, McElduff N, Jones MC: Calcium acetate versus calcium carbonate as phosphate-binding agents in chronic haemodialysis. Nephrol Dial Transplant 9:1121-1124, 1994
155. Ring T, Nielsen C, Andersen SP, Behrens JK, Sodemann B, Kornerup HJ: Calcium acetate versus calcium carbonate as phosphorus binders in patients on chronic haemodialysis: A controlled study. Nephrol Dial Transplant 8:341-346, 1993
156. Caravaca F, Fernandez MA, Ruiz-Calero R, Cubero J, Aparicio A, Jimenez F, Garcia MC: Effects of oral phosphorus supplementation on mineral metabolism of renal transplant recipients. Nephrol Dial Transplant 13:2605-2611, 1998
157. Chertow GM, Burke SK, Lazarus JM, Stenzel KH, Wombolt D, Goldberg D, Bonventre JV, Slatopolsky E: Poly[allylamine hydrochloride](RenaGel): A noncalcemic phosphate binder for the treatment of hyperphosphatemia in chronic renal failure. Am J Kidney Dis 29:66-71, 1997
158. Delmez JA, Kelber J, Norword KY, Giles KS, Slatopolsky E: Magnesium carbonate as a phosphorus binder: A prospective, controlled, crossover study. Kidney Int 49:163-167, 1996
159. van den Bergh JP, Gelens MA, Klaassen HA, Kaufmann BG, Bottger WM, Verstappen VM: Efficacy and tolerance of three different calcium acetate formulations in hemodialysis patients. Neth J Med 55:222-228, 1999
160. Tan SY, Irish A, Winearls CG, Brown EA, Gower PE, Clutterbuck EJ, Madhoo S, Lavender JP, Pepys MB, Hawkins PN: Long term effect of renal transplantation on dialysis-related amyloid deposits and symptomatology. Kidney Int 50:282-289, 1996
161. Ittel TH, Schafer C, Schmitt H, Gladziwa U, Sieberth HG: Calcium carbonate as a phosphate binder in dialysis patients: Evaluation of an enteric-coated preparation and effect of additional aluminium hydroxide on hyperaluminaemia. Klin Wochenschr 69:59-67, 1991
162. Bro S, Rasmussen RA, Handberg J, Olgaard K, Feldt-Rasmussen B: Randomized crossover study comparing the phosphate-binding efficacy of calcium ketoglutarate versus calcium carbonate in patients on chronic hemodialysis. Am J Kidney Dis 31:257-262, 1998
163. Jespersen B, Jensen JD, Nielsen HK, Lauridsen IN, Andersen MJ, Poulsen JH, Gammelgaard B, Pedersen EB: Comparison of calcium carbonate and aluminium hydroxide as phosphate binders on biochemical bone markers, PTH(1-84), and bone mineral content in dialysis patients. Nephrol Dial Transplant 6:98-104, 1991
164. Bame SI, Petersen N, Wray NP: Variation in hemodialysis patient compliance according to demographic characteristics. Soc Sci Med 37:1035-1043, 1993
165. Coyne T, Olson M, Bradham K, Garcon M, Gregory P, Scherch L: Dietary satisfaction correlated with adherence in the Modification of Diet in Renal Disease Study. J Am Diet Assoc 95:1301-1306, 1995
166. Cleary DJ, Matzke GR, Alexander AC, Joy MS: Medication knowledge and compliance among patients receiving long-term dialysis. Am J Health Syst Pharm 52:1895-1900, 1995
167. Morduchowicz G, Sulkes J, Aizic S, Gabbay U, Winkler J, Boner G: Compliance in hemodialysis patients: A multivariate regression analysis. Nephron 64:365-368, 1993
168. Weed-Collins M, Hogan R: Knowledge and health beliefs regarding phosphate-binding medication in predicting compliance. Anna J 16:278-282285, discussion 286, 1989
169. Cummings KM, Becker MH, Kirscht JP, Levin NW: Psychosocial factors affecting adherence to medical regiments in a group of hemodialysis patients. Med Care 20:567-580, 1982
170. Blackburn SL: Dietary compliance of chronic hemodialysis patients. J Am Diet Assoc 70:31-37, 1977
171. Coburn JW, Mischel MG, Goodman WG, Salusky IB: Calcium citrate markedly enhances aluminum absorption from aluminum hydroxide. Am J Kidney Dis 17:708-711, 1991
172. Chertow GM, Dillon M, Burke SK, Steg M, Bleyer AJ, Garrett BN, Domoto DT, Wilkes BM, Wombolt DG, Slatopolsky E: A randomized trial of sevelamer hydrochloride (RenaGel) with and without supplemental calcium. Strategies for the control of hyperphosphatemia and hyperparathyroidism in hemodialysis patients. Clin Nephrol 51:18-26, 1999
173. Chertow GM, Dillon MA, Amin N, Burke SK: Sevelamer with and without calcium and vitamin D: Observations from a long-term open-label clinical trial. J Ren Nutr 10:125-132, 2000
174. Kurz P, Monier-Faugere MC, Bognar B, Werner E, Roth P, Vlachojannis J, Malluche HH: Evidence for abnormal calcium homeostasis in patients with adynamic bone disease. Kidney Int 46:855-861, 1994
175. Chertow GM, Burke SK, Raggi P: Sevelamer attenuates the progression of coronary and aortic calcification in hemodialysis patients. Kidney Int 62:245-252, 2002
176. Nordin BEC: Nutritional consideration, in Nordin BEC (ed): Calcium, Phosphate and Magnesium Metabolism. New York, NY, Churchill Livingston, 1976, pp 3-35
177. Elin RJ: Laboratory reference intervals and values, in Goldman L, Bennett JC (eds): Cecil Textbook of Medicine (ed 21). Philadelphia, PA, Saunders, 2000, pp 2299-2308
178. Enders DB, Rude RK: Mineral and bone metabolism, in Burtis CA, Ashwood ER (ed): Tietz Fundamentals of Clinical Chemistry (ed 5). Philadelphia, PA, Saunders, 2001, pp 795-821
179. Portale AA: Blood calcium, phosphorus, and magnesium, in Favus MJ (ed): Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. Philadelphia, PA, Lippincott, Williams & Wilkins, 1999, pp 115-118
180. Institute of Medicine: Dietary References Intakes: Calcium, Phosphorus, Magnesium, Vitamin D3, and Fluoride. Washington, DC, National Academy Press, 1997
181. Lemann J, Favus MJ: The intestinal absorption of calcium, magnesium, and phosphate, in Favus MJ (ed): Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. Philadelphia, PA, Lippincott, Williams & Wilkins, 1999, pp 63-67
182. Brickman AS, Coburn JW, Massry SG, Norman AW: 1,25 Dihydroxy-vitamin D3 in normal man and patients with renal failure. Ann Intern Med 80:161-168, 1974
183. Shane E: Hypercalcemia; pathogenesis, clinical manifestation, differential diagnosis and management, in Favus MJ (ed): Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism. Philadelphia, PA, Lippincott, Williams & Wilkins, 1999, pp 183-187
184. Massry SG, Smogorzewski M: Dyscalcemias, in Massry SG, Glassock RJ (eds): Massry and Glassocks Textbook of Nephrology. Philadelphia, PA, Lippincott, Williams & Wilkins, 2001, 326-340
185. Fernandez E, Montoliu J: Successful treatment of massive uraemic tumoral calcinosis with daily haemodialysis and very low calcium dialysate. Nephrol Dial Transplant 9:1207-1209, 1994
186. Clase CM, Norman GL, Beecroft ML, Churchill DN: Albumin-corrected calcium and ionized calcium in stable haemodialysis patients. Nephrol Dial Transplant 15:1841-1846, 2000
187. Morton AR, Hercz G: Hypercalcemia in dialysis patients: Comparison of diagnostic methods. Dial Transplant 20:661-667, 1991
188. Coburn JW, Popovtzer MM, Massry SG, Kleeman CR: The physicochemical state and renal handling of divalent ions in chronic renal failure. Arch Intern Med 124:302-311, 1969
189. Wasler M: The separate effects of hyperparathyroidism, hypercalcemia of malignancy, renal failure and acidosis on the state of calcium phosphate and other ions in plasma. J Clin Invest 41:1454-1464, 1962
190. Campos C, Arata RO, Mautalen CA: Parathyroid hormone and vertebral osteosclerosis in uremic patients. Metabolism 25:495-501, 1976
191. Fuss M, De Backer M, Brauman J, Nijs-Dewolf N, Manderlier T, Brauman H, Corvilain J: Parathyroid hormone plasma level in untreated chronic renal failure and in hemodialyzed patients. Nephron 17:144-154, 1976
192. Malhotra KK, Gadekar NG, Umashankar P, Bhargava S: Bone disease in chronic renal failure. Indian J Med Res 56:1687-1695, 1968
193. Foley RN, Parfrey PS, Harnett JD, Kent GM, Hu L, ODea R, Murray DC, Barre PE: Hypocalcemia, morbidity, and mortality in end-stage renal disease. Am J Nephrol 16:386-393, 1996
194. Malluche HH, Werner E, Ritz E: Intestinal calcium absorption and whole-body calcium retention incipient and advanced renal failure. Miner Electrolyte Metab 1:263-270, 1978
195. Coburn JW, Koppel MH, Brickman AS, Massry SG: Study of intestinal absorption of calcium in patients with renal failure. Kidney Int 3:264-272, 1973
196. Wiegmann TB, Kaye M: Malabsorption of calcium and phosphate in chronic renal failure: 32P and 45Ca studies in dialysis patients. Clin Nephrol 34:35-41, 1990
197. Mountokalakis TH, Singhellakis PN, Alevizaki CC, Virvidakis K, Ikkos DG: Relationship between degree of renal failure and impairment of intestinal calcium absorption. Nephron 16:20-30, 1976
198. Kopple JD, Coburn JW: Metabolic studies of low protein diets in uremia. II. Calcium, phosphorus and magnesium. Medicine (Baltimore) 52:597-607, 1973
199. Popovtzer MM, Michael UF, Johnson-Dial KS, Ronstadt C, Nelson D, Ogden DA: Dietary calcium deprivation and secondary hyperparathyroidism in patients treated with chronic dialysis. Miner Electrolyte Metab 12:298-302, 1986
200. Trachtman H, Chan JC, Boyle R, Farina D, Baluarte HJ, Chinchilli VM, Dresner IG, Feld LG: The relationship between calcium, phosphorus, and sodium intake, race, and blood pressure in children with renal insufficiency: A report of the Growth Failure in Children with Renal Diseases (GFRD) Study. J Am Soc Nephrol 6:126-131, 1995
201. Clarkson EM, Eastwood JB, Koutsaimanis KG, de Wardener HE: Net intestinal absorption of calcium in patients with chronic renal failure.Kidney Int 3:258-263, 1973
202. Friis T, Hahnemann S, Weeke E: Serum calcium and serum phsophorus in uraemia during administration of osdium phytate and aluminium hydroxide. Acta Med Scand 183:497-505, 1968
203. Hercz G, Kraut JA, Andress DA, Howard N, Roberts C, Shinaberger JH, Sherrard DJ, Coburn JW: Use of calcium carbonate as a phosphate binder in dialysis patients. Miner Electrolyte Metab 12:314-319, 1986
204. Moriniere P, Fournier A, Leflon A, Herve M, Sebert JL, Gregoire I, Bataille P, Gueris J: Comparison of 1 alpha-OH-vitamin D3 and high doses of calcium carbonate for the control of hyperparathyroidism and hyperaluminemia in patients on maintenance dialysis. Nephron 39:309-315, 1985
205. Petersen LJ, Rudnicki M, Hojsted J: Long-term oral calcium supplementation reduces diastolic blood pressure in end stage renal disease. A randomized, double-blind, placebo controlled study. Int J Artif Organs 17:37-40, 1994
206. Saha H, Pietila K, Mustonen J, Pasternack A, Morsky P, Seppala E, Reinikainen P: Acute effects of calcium carbonate and citrate on secondary hyperparathyroidism in chronic renal failure. Am J Nephrol 11:465-469, 1991
207. Maher ER, Young G, Smyth-Walsh B, Pugh S, Curtis JR: Aortic and mitral valve calcification in patients with end-stage renal disease. Lancet 2:875-877, 1987
208. Fernandez-Reyes MJ, Auxiliadora Bajo M, Robles P, Selgas R, Oliver J, Del Peso G, Garcia G, Jimenez C, Garcia-Gallego F: Mitral annular calcification in CAPD patients with a low degree of hyperparathyroidism. An analysis of other possible risk factors. Nephrol Dial Transplant 10:2090-2095, 1995
209. Valentzas C, Meindok H, Oreopoulos DG, Meema HK, Rabinovich S, Jones M, Sutton D, Rapaport A, deVeber GA: Visceral calcification and Ca-P product. Adv Exp Med Biol 103:187-193, 1978
210. Ribeiro S, Ramos A, Brandao A, Rebelo JR, Guerra A, Resina C, Vila-Lobos A, Carvalho F, Remedio F, Ribeiro F: Cardiac valve calcification in haemodialysis patients: Role of calcium-phosphate metabolism. Nephrol Dial Transplant 13:2037-2040, 1998
211. Cassidy MJ, Owen JP, Ellis HA, Dewar J, Robinson CJ, Wilkinson R, Ward MK, Kerr DN: Renal osteodystrophy and metastatic calcification in long-term continuous ambulatory peritoneal dialysis. Q J Med 54:29-48, 1985
212. Bouillon RA, Auwerx JH, Lissens WD, Pelemans WK: Vitamin D status in the elderly: Seasonal substrate deficiency causes 1,25-dihydroxycholecalciferol deficiency. Am J Clin Nutr 45:755-763, 1987
213. Ooms ME, Roos JC, Bezemer PD, van der Vijgh WJ, Bouter LM, Lips P: Prevention of bone loss by vitamin D supplementation in elderly women: A randomized double-blind trial. J Clin Endocrinol Metab 80:1052-1058, 1995
214. Khaw KT, Sneyd MJ, Compston J: Bone density, parathyroid hormone and 25-hydroxyvitamin D concentrations in middle aged women. Br Med J 305:373-376, 1992
215. Eastwood JB, Stamp TC, De Wardener HE, Bordier PJ, Arnaud CD: The effect of 25-hydroxy vitamin D3 in the osteomalacia of chronic renal failure. Clin Sci Mol Med 52:499-508, 1977
216. Eastwood JB, Stamp TC, Harris E, de Wardener HE: Vitamin-D deficiency in the osteomalacia of chronic renal failure. Lancet 2:1209-1211, 1976
217. Chapuy MC, Meunier PJ: Vitamin D insufficiency in adults and the elderly, in Feldman D, Glorieux FH, Pike JW (eds): Vitamin D. San Diego, CA, Academic, 1997, pp 679-693
218. Thomas MK, Lloyd-Jones DM, Thadhani RI, Shaw AC, Deraska DJ, Kitch BT, Vamvakas EC, Dick IM, Prince RL, Finkelstein JS: Hypovitaminosis D in medical inpatients. N Engl J Med 338:777-783, 1998
219. LeBoff MS, Kohlmeier L, Hurwitz S, Franklin J, Wright J, Glowacki J: Occult vitamin D deficiency in postmenopausal US women with acute hip fracture. JAMA 281:1505-1511, 1999
220. Koenig KG, Lindberg JS, Zerwekh JE, Padalino PK, Cushner HM, Copley JB: Free and total 1,25-dihydroxyvitamin D levels in subjects with renal disease. Kidney Int 41:161-165, 1992
221. Papapoulos SE, Clemens TL, Fraher LJ, Gleed J, ORiordan JL: Metabolites of vitamin D in human vitamin-D deficiency: Effect of vitamin D3 or 1,25-dihydroxycholecalciferol. Lancet 2:612-615, 1980
222. Holick MF: Vitamin D and the kidney. Kidney Int 32:912-929, 1987
223. Holick MF, Matsuoka LY, Wortsman J: Age, vitamin D, and solar ultraviolet. Lancet 2:1104-1105, 1989
224. Clemens TL, Adams JS, Henderson SL, Holick MF: Increased skin pigment reduces the capacity of skin to synthesise vitamin D3. Lancet 1:74-76, 1982
225. Chapuy MC, Preziosi P, Maamer M, Arnaud S, Galan P, Hercberg S, Meunier PJ: Prevalence of vitamin D insufficiency in an adult normal population. Osteoporos Int 7:439-443, 1997
226. Saha H: Calcium and vitamin D homeostasis in patients with heavy proteinuria. Clin Nephrol 41:290-296, 1994
227. Kinyamu HK, Gallagher JC, Balhorn KE, Petranick KM, Rafferty KA: Serum vitamin D metabolites and calcium absorption in normal young and elderly free-living women and in women living in nursing homes. Am J Clin Nutr 65:790-797, 1997
228. Webb AR, Pilbeam C, Hanafin N, Holick MF: An evaluation of the relative contributions of exposure to sunlight and of diet to the circulating concentrations of 25-hydroxyvitamin D in an elderly nursing home population in Boston. Am J Clin Nutr 51:1075-1081, 1990
229. Ghazali A, Fardellone P, Pruna A, Atik A, Achard JM, Oprisiu R, Brazier M, Remond A, Moriniere P, Garabedian M, Eastwood J, Fournier A: Is low plasma 25-(OH)vitamin D a major risk factor for hyperparathyroidism and Loosers zones independent of calcitriol? Kidney Int 55:2169-2177, 1999
230. Lambert PW, Stern PH, Avioli RC, Brackett NC, Turner RT, Greene A, Fu IY, Bell NH: Evidence for extrarenal production of 1 alpha,25-dihydroxyvitamin D in man. J Clin Invest 69:722-725, 1982
231. Dusso A, Lopez-Hilker S, Rapp N, Slatopolsky E: Extra-renal production of calcitriol in chronic renal failure. Kidney Int 34:368-375, 1988
232. Dusso AS, Finch J, Brown A, Ritter C, Delmez J, Schreiner G, Slatopolsky E: Extrarenal production of calcitriol in normal and uremic humans. J Clin Endocrinol Metab 72:157-164, 1991
233. Food and Nutrition Board. National Research Council. National Academy of Sciences. Recommended Daily Allowances (ed 10). Washington, DC, National Academy Press, 1989
234. Food and Nutrition Board. National Research Council. National Academy of Sciences. Dietary Reference Intakes for Calcium, Phosphorus, Magnesium, Vitamin D, and Fluoride. Washington, DC, National Academy Press, 1997
235. Shah BR, Finberg L: Single-day therapy for nutritional vitamin D-deficiency rickets: A preferred method. J Pediatr 125:487-490, 1994
236. Kruse K: Pathophysiology of calcium metabolism in children with vitamin D-deficiency rickets. J Pediatr 126:736-741, 1995
237. Combe C, Aparicio M: Phosphorus and protein restriction and parathyroid function in chronic renal failure. Kidney Int 46:1381-1386, 1994
238. Lafage MH, Combe C, Fournier A, Aparicio M: Ketodiet, physiological calcium intake and native vitamin D improve renal osteodystrophy. Kidney Int 42:1217-1225, 1992
239. Coburn JW, Tan AU Jr, Levine BS, Mazess RB, Kyllo DM, Knutson JC, Bishop CW: 1 alpha-Hydroxy-vitamin D2: A new look at an old compound. Nephrol Dial Transplant 11:153-157, 1996 (suppl 3)
240. Harrington DD, Page EH: Acute vitamin D3 toxicosis in horses: Case reports and experimental studies of the comparative toxicity of vitamins D2 and D3. J Am Vet Med Assoc 182:1358-1369, 1983
241. van der Wielen RP, Lowik MR, van den Berg H, de Groot LC, Haller J, Moreiras O, van Staveren WA: Serum vitamin D concentrations among elderly people in Europe. Lancet 346:207-210, 1995
242. Lips P, van Ginkel FC, Jongen MJ, Rubertus F, van der Vijgh WJ, Netelenbos JC: Determinants of vitamin D status in patients with hip fracture and in elderly control subjects. Am J Clin Nutr 46:1005-1010, 1987
243. Chapuy MC, Arlot ME, Duboeuf F, Brun J, Crouzet B, Arnaud S, Delmas PD, Meunier PJ: Vitamin D3 and calcium to prevent hip fractures in the elderly women. N Engl J Med 327:1637-1642, 1992
244. Prince RL, Hutchison BG, Kent JC, Kent GN, Retallack RW: Calcitriol deficiency with retained synthetic reserve in chronic renal failure. Kidney Int 33:722-728, 1988
245. Rickers H, Christiansen C, Christensen P, Christensen M, Rodbro P: Serum concentrations of vitamin D metabolites in different degrees of impaired renal function. Estimation of renal and extrarenal secretion rate of 24,25-dihydroxyvitamin D. Nephron 39:267-271, 1985
246. Nordal KP, Dahl E: Low dose calcitriol versus placebo in patients with predialysis chronic renal failure. J Clin Endocrinol Metab 67:929-936, 1988
247. Coen G, Mazzaferro S, Bonucci E, Ballanti P, Massimetti C, Donato G, Landi A, Smacchi A, Della Rocca C, Cinotti GA, et al: Treatment of secondary hyperparathyroidism of predialysis chronic renal failure with low doses of 1,25(OH)2D3: Humoral and histomorphometric results. Miner Electrolyte Metab 12:375-382, 1986
248. Bianchi ML, Colantonio G, Campanini F, Rossi R, Valenti G, Ortolani S, Buccianti G: Calcitriol and calcium carbonate therapy in early chronic renal failure. Nephrol Dial Transplant 9:1595-1599, 1994
249. Portale AA, Booth BE, Halloran BP, Morris RC Jr: Effect of dietary phosphorus on circulating concentrations of 1,25-dihydroxyvitamin D and immunoreactive parathyroid hormone in children with moderate renal insufficiency. J Clin Invest 73:1580-1589, 1984
250. Silver J, Naveh-Many T, Mayer H, Schmelzer HJ, Popovtzer MM: Regulation by vitamin D metabolites of parathyroid hormone gene transcription in vivo in the rat. J Clin Invest 78:1296-1301, 1986
251. Przedlacki J, Manelius J, Huttunen K: Bone mineral density evaluated by dual-energy X-ray absorptiometry after one-year treatment with calcitriol started in the predialysis phase of chronic renal failure. Nephron 69:433-437, 1995
252. Baker LR, Abrams L, Roe CJ, Faugere MC, Fanti P, Subayti Y, Malluche HH: 1,25(OH)2D3 administration in moderate renal failure: A prospective double-blind trial. Kidney Int 35:661-669, 1989
253. Nordal KP, Dahl E, Halse J, Attramadal A, Flatmark A: Long-term low-dose calcitriol treatment in predialysis chronic renal failure: Can it prevent hyperparathyroid bone disease? Nephrol Dial Transplant 10:203-206, 1995
254. Coen G, Mazzaferro S, Manni M, Napoletano I, Fondi G, Sardella D, Perruzza I, Pasquali M, Taggi F: Treatment with small doses of 1,25-dihydroxyvitamin D in predialysis chronic renal failure may lower the rate of decline of renal function. Ital J Miner Electrolyte Metab 8:117-121, 1994
255. Jensen GF, Christiansen C, Transbol I: 1,25(OH)2D3 and renal function. A controlled clinical study in normal elderly women. Acta Med Scand 211:51-54, 1982
256. Bertoli M, Luisetto G, Ruffatti A, Urso M, Romagnoli G: Renal function during calcitriol therapy in chronic renal failure. Clin Nephrol 33:98-102, 1990
257. Perez A, Raab R, Chen TC, Turner A, Holick MF: Safety and efficacy of oral calcitriol (1,25-dihydroxyvitamin D3) for the treatment of psoriasis. Br J Dermatol 134:1070-1078, 1996
258. Kanis JA, Cundy T, Earnshaw M, Henderson RG, Heynen G, Naik R, Russell RG, Smith R, Woods CG: Treatment of renal bone disease with 1 alpha-hydroxylated derivatives of vitamin D3. Clinical, biochemical, radiographic and histological responses. Q J Med 48:289-322, 1979
259. Naik RB, Cundy T, Robinson BH, Russell RG, Kanis JA: Effects of vitamin D metabolites and analogues on renal function. Nephron 28:17-25, 1981
260. Nielsen HE, Romer FK, Melsen F, Christensen MS, Hansen HE: 1 alpha-hydroxy vitamin D3 treatment of non-dialyzed patients with chronic renal failure. Effects on bone, mineral metabolism and kidney function. Clin Nephrol 13:103-108, 1980
261. Brickman AS, Coburn JW, Sherrard DJ, Wong EG, Norman AW, Singer FR: Clinical effects of 1,25-dihydroxyvitamin D3 in uremic patients with overt osteodystrophy. Contrib Nephrol 18:29-41, 1980
262. Kanis JA, Russell RG, Cundy T, Earnshaw M, Woods CG, Smith R, Heynen G: An evaluation of 1 alpha-hydroxy-and 1,25-dihydroxyvitamin D3 in the treatment of renal bone disease. Contrib Nephrol 18:12-28, 1980
263. Berl T, Berns AS, Huffer WE, Alfrey AC, Arnaud CD, Schrier RR: Controlled trial of the effects of 1,25-dihydroxycholecalciferol in patients treated with regular dialysis. Contrib Nephrol 18:72-81, 1980
264. Peacock M, Aaron JE, Walker GS, Davison AM: Bone disease and hyperparathyroidism in chronic renal failure: the effect of 1alpha-hydroxyvitamin D3. Clin Endocrinol (Oxf) 7:73s-81s, 1977 (suppl)
265. Herrmann P, Ritz E, Schmidt-Gayk H, Schafer I, Geyer J, Nonnast-Daniel B, Koch KM, Weber U, Horl W, Haas-Worle A, et al: Comparison of intermittent and continuous oral administration of calcitriol in dialysis patients: A randomized prospective trial. Nephron 67:48-53, 1994
266. Papapoulos SE, Brownjohn AM, Junor BJ, Marsh FP, Goodwin FJ, Hately W, Lewin IG, Tomlinson S, Hendy GN, ORiordan JL: Hyperparathyroidism in chronic renal failure. Clin Endocrinol (Oxf) 7:59s-65s, 1977 (suppl)
267. Moriniere P, Esper NE, Viron B, Judith D, Bourgeon B, Farquet C, Gheerbrandt JD, Chapuy MC, Orshoven AV, Pamphile R, Fournier A: Improvement of severe secondary hyperparathyroidism in dialysis patients by intravenous 1-alpha(OH) vitamin D3, oral CaCo3 and low dialysate calcium. Kidney Int 43:S121-S124, 1993 (suppl 41)
268. Morii H, Ogura Y, Koshikawa S, Mimura N, Suzuki M, Kurokawa K, Marumo F, Kawaguchi Y, Maeda K, Nishizawa Y, Inoue S, Fujima S: Efficacy and safety of oral falecalcitrol in reducing parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism. J Bone Miner Metab 16, 1988
269. Frazao JM, Elangovan L, Maung HM, Chesney RW, Acchiardo SR, Bower JD, Kelley BJ, Rodriguez HJ, Norris KC, Robertson JA, Levine BS, Goodman WG, Gentile D, Mazess RB, Kyllo DM, Douglass LL, Bishop CW, Coburn JW: Intermittent doxercalciferol (1alpha-hydroxyvitamin D(2)) therapy for secondary hyperparathyroidism. Am J Kidney Dis 36:550-561, 2000
270. Maung HM, Elangovan L, Frazao JM, Bower JD, Kelley BJ, Acchiardo SR, Rodriguez HJ, Norris KC, Sigala JF, Rutkowski M, Robertson JA, Goodman WG, Levine BS, Chesney RW, Mazess RB, Kyllo DM, Douglass LL, Bishop CW, Coburn JW: Efficacy and side effects of intermittent intravenous and oral doxercalciferol (1alpha-hydroxyvitamin D(2)) in dialysis patients with secondary hyperparathyroidism: A sequential comparison. Am J Kidney Dis 37:532-543, 2001
271. Sherrard DJ, Coburn JW, Brickman AS, Singer FR, Maloney N: Skeletal response to treatment with 1,25-dihydroxyvitamin D in renal failure. Contrib Nephrol 18:92-97, 1980
272. Krempien B, Ritz E, Tschope W: The effect of 1,25 (OH)2D3 on bone mineralization: Ultrastructural studies in patients with renal osteodystrophy. Contrib Nephrol 18:122-134, 1980
273. Tan AU Jr, Levine BS, Mazess RB, Kyllo DM, Bishop CW, Knutson JC, Kleinman KS, Coburn JW: Effective suppression of parathyroid hormone by 1 alpha-hydroxy-vitamin D2 in hemodialysis patients with moderate to severe secondary hyperparathyroidism. Kidney Int 51:317-323, 1997
274. Quarles LD, Lobaugh B, Murphy G: Intact parathyroid hormone overestimates the presence and severity of parathyroid-mediated osseous abnormalities in uremia. J Clin Endocrinol Metab 75:145-150, 1992
275. Sprague SM, Moe SM: Safety and efficacy of long-term treatment of secondary hyperparathyroidism by low-dose intravenous calcitriol. Am J Kidney Dis 19:532-539, 1992
276. Cannella G, Bonucci E, Rolla D, Ballanti P, Moriero E, De Grandi R, Augeri C, Claudiani F, Di Maio G: Evidence of healing of secondary hyperparathyroidism in chronically hemodialyzed uremic patients treated with long-term intravenous calcitriol. Kidney Int 46:1124-1132, 1994
277. Dressler R, Laut J, Lynn RI, Ginsberg N: Long-term high dose intravenous calcitriol therapy in end-stage renal disease patients with severe secondary hyperparathyroidism. Clin Nephrol 43:324-331, 1995
278. Llach F, Hervas J, Cerezo S: The importance of dosing intravenous calcitriol in dialysis patients with severe hyperparathyroidism. Am J Kidney Dis 26:845-851, 1995
279. Fukuda N, Tanaka H, Tominaga Y, Fukagawa M, Kurokawa K, Seino Y: Decreased 1,25-dihydroxyvitamin D3 receptor density is associated with a more severe form of parathyroid hyperplasia in chronic uremic patients. J Clin Invest 92:1436-1443, 1993
280. Fukagawa M, Kitaoka M, Yi H, Fukuda N, Matsumoto T, Ogata E, Kurokawa K: Serial evaluation of parathyroid size by ultrasonography is another useful marker for the long-term prognosis of calcitriol pulse therapy in chronic dialysis patients. Nephron 68:221-228, 1994
281. Fukagawa M, Okazaki R, Takano K, Kaname S, Ogata E, Kitaoka M, Harada S, Sekine N, Matsumoto T, Kurokawa K: Regression of parathyroid hyperplasia by calcitriol-pulse therapy in patients on long-term dialysis. N Engl J Med 323:421-422, 1990
282. Tsukamoto Y, Nomura M, Takahashi Y, Takagi Y, Yoshida A, Nagaoka T, Togashi K, Kikawada R, Marumo F: The oral 1,25-dihydroxyvitamin D3 pulse therapy in hemodialysis patients with severe secondary hyperparathyroidism. Nephron 57:23-28, 1991
283. Muramoto H, Haruki K, Yoshimura A, Mimo N, Oda K, Tofuku Y: Treatment of refractory hyperparathyroidism in patients on hemodialysis by intermittent oral administration of 1,25(OH)2vitamin D3. Nephron 58:288-294, 1991
284. Baker LR, Muir JW, Sharman VL, Abrams SM, Greenwood RN, Cattell WR, Goodwin FJ, Marsh FP, Adami S, Hately W, et al: Controlled trial of calcitriol in hemodialysis patients. Clin Nephrol 26:185-191, 1986
285. Memmos DE, Eastwood JB, Talner LB, Gower PE, Curtis JR, Phillips ME, Carter GD, Alaghband-Zadeh J, Roberts AP, de Wardener HE: Double-blind trial of oral 1,25-dihydroxy vitamin D3 versus placebo in asymptomatic hyperparathyroidism in patients receiving maintenance haemodialysis. Br Med J (Clin Res Ed) 282:1919-1924, 1981
286. Bacchini G, Fabrizi F, Pontoriero G, Marcelli D, Di Filippo S, Locatelli F: Pulse oral versus intravenous calcitriol therapy in chronic hemodialysis patients. A prospective and randomized study. Nephron 77:267-272, 1997
287. Indridason OS, Quarles LD: Comparison of treatments for mild secondary hyperparathyroidism in hemodialysis patients. Durham Renal Osteodystrophy Study Group. Kidney Int 57:282-292, 2000
288. Fischer ER, Harris DC: Comparison of intermittent oral and intravenous calcitriol in hemodialysis patients with secondary hyperparathyroidism. Clin Nephrol 40:216-220, 1993
289. Liou HH, Chiang SS, Huang TP, Shieh SD, Akmal M: Comparative effect of oral or intravenous calcitriol on secondary hyperparathyroidism in chronic hemodialysis patients. Miner Electrolyte Metab 20:97-102, 1994
290. Caravaca F, Cubero JJ, Jimenez F, Lopez JM, Aparicio A, Cid MC, Pizarro JL, Liso J, Santos I: Effect of the mode of calcitriol administration on PTH-ionized calcium relationship in uraemic patients with secondary hyperparathyroidism. Nephrol Dial Transplant 10:665-670, 1995
291. Quarles LD, Yohay DA, Carroll BA, Spritzer CE, Minda SA, Bartholomay D, Lobaugh BA: Prospective trial of pulse oral versus intravenous calcitriol treatment of hyperparathyroidism in ESRD. Kidney Int 45:1710-1721, 1994
292. Levine BS, Song M: Pharmacokinetics and efficacy of pulse oral versus intravenous calcitriol in hemodialysis patients. J Am Soc Nephrol 7:488-496, 1996
293. Gallieni M, Brancaccio D, Padovese P, Rolla D, Bedani P, Colantonio G, Bronzieri C, Bagni B, Tarolo G: Low-dose intravenous calcitriol treatment of secondary hyperparathyroidism in hemodialysis patients. Italian Group for the Study of Intravenous Calcitriol. Kidney Int 42:1191-1198, 1992
294. Moe SM, Kraus MA, Gassensmith CM, Fineberg NS, Gannon FH, Peacock M: Safety and efficacy of pulse and daily calcitriol in patients on CAPD: A randomized trial. Nephrol Dial Transplant 13:1234-1241, 1998
295. Brown AJ, Slatopolsky E: Vitamin D analogs: Perspectives for treatment. Miner Electrolyte Metab 25:337-341, 1999
296. Slatopolsky E, Dusso A, Brown A: New analogs of vitamin D3. Kidney Int Suppl 73:S46-S51, 1999
297. Kurokawa K, Akizawa T, Suzuki M, Akiba T, Ogata E, Slatopolsky E: Effect of 22-oxacalcitriol on hyperparathyroidism of dialysis patients: Results of a preliminary study. Nephrol Dial Transplant 11:121-124, 1996 (suppl 3)
298. Akiba T, Marumo F, Owada A, Kurihara S, Inoue A, Chida Y, Ando R, Shinoda T, Ishida Y, Ohashi Y: Controlled trial of falecalcitriol versus alfacalcidol in suppression of parathyroid hormone in hemodialysis patients with secondary hyperparathyroidism. Am J Kidney Dis 32:238-246, 1998
299. Taga T: The signal transducer gp130 is shared by interleukin-6 family of haematopoietic and neurotrophic cytokines. Ann Med 29:63-72, 1997
300. Slatopolsky E, Finch J, Ritter C, Denda M, Morrissey J, Brown A, DeLuca H: A new analog of calcitriol, 19-nor-1,25-(OH)2D2, suppresses parathyroid hormone secretion in uremic rats in the absence of hypercalcemia. Am J Kidney Dis 26:852-860, 1995
301. Nishii Y, Abe J, Mori T, Brown AJ, Dusso AS, Finch J, Lopez-Hilker S, Morrissey J, Slatopolsky E: The noncalcemic analogue of vitamin D, 22-oxacalcitriol, suppresses parathyroid hormone synthesis and secretion. Contrib Nephrol 91:123-128, 1991
302. Sjoden G, Lindgren JU, DeLuca HF: Antirachitic activity of 1 alpha-hydroxyergocalciferol and 1 alpha-hydroxycholecalciferol in rats. J Nutr 114:2043-2046, 1984
303. Sjoden G, Smith C, Lindgren U, DeLuca HF: 1 alpha-Hydroxyvitamin D2 is less toxic than 1 alpha-hydroxyvitamin D3 in the rat. Proc Soc Exp Biol Med 178:432-436, 1985
304. Gallagher JC, Bishop CW, Knutson JC, Mazess RB, DeLuca HF: Effects of increasing doses of 1 alpha-hydroxyvitamin D2 on calcium homeostasis in postmenopausal osteopenic women. J Bone Miner Res 9:607-614, 1994
305. Weber K, Goldberg M, Stangassinger M, Erben RG: 1alpha-hydroxyvitamin D2 is less toxic but not bone selective relative to 1alpha-hydroxyvitamin D3 in ovariectomized rats. J Bone Miner Res 16:639-651, 2001
306. Vlassopoulos D, Noussias C, Revenas K, Hadjilouka-Mantaka A, Arvanitis D, Tzortzis G, Hadjiconstantinou V: Long-term effects of small doses of calcitriol in hemodialysis patients with moderate secondary hyperparathyroidism. Ren Fail 21:199-207, 1999
307. Martinez ME, Selgas R, Miguel JL, Balaguer G, Sanchez-Cabezudo MJ, Llach F: Osteocalcin levels in uremic patients: influence of calcitriol treatment through two different routes and type of dialysis. Nephron 59:429-433, 1991
308. Morita A, Tabata T, Inoue T, Nishizawa Y, Morii H: The effect of oral 1 alpha-hydroxycalciferol treatment on bone mineral density in hemodialysis patients. Clin Nephrol 46:389-393, 1996
309. Shimamatsu K, Maeda T, Harada A, Nishitani H, Onoyama K, Fujimi S, Omae T: 1-year controlled trial of 1 alpha-hydroxycholecalciferol in patients on maintenance hemodialysis. Nephron 28:70-75, 1981
310. Goodman WG, Ramirez JA, Belin TR, Chon Y, Gales B, Segre GV, Salusky IB: Development of adynamic bone in patients with secondary hyperparathyroidism after intermittent calcitriol therapy. Kidney Int 46:1160-1166, 1994
311. Kuizon BD, Goodman WG, Juppner H, Boechat I, Nelson P, Gales B, Salusky IB: Diminished linear growth during intermittent calcitriol therapy in children undergoing CCPD. Kidney Int 53:205-211, 1998
312. Andress DL, Norris KC, Coburn JW, Slatopolsky EA, Sherrard DJ: Intravenous calcitriol in the treatment of refractory osteitis fibrosa of chronic renal failure. N Engl J Med 321:274-279, 1989
313. Kanis JA, Russell RG, Naik RB, Earnshaw M, Smith R, Heynen G, Woods CG: Factors influencing the response to 1alpha-hydroxyvitamin D3 in patients with renal bone disease. Clin Endocrinol (Oxf) 7:51s-57s, 1977 (suppl)
314. Malluche HH, Goldstein DA, Massry SG: Effects of 6 months therapy with 1,25 (OH)2D3 on bone disease of dialysis patients. Contrib Nephrol 18:98-104, 1980
315. Delling G, Luhmann H, Bulla M, Fuchs C, Henning HV, Jansen JL, Kohnle W, Schulz W: The action of 1,25 (OH)2D3 on turnover kinetic, remodelling surfaces and structure of trabecular bone in chronic renal failure. Contrib Nephrol 18:105-121, 1980
316. Johnson WJ, Goldsmith RS, Beabout JW, Jowsey J, Kelly PJ, Arnaud CD: Prevention and reversal of progressive secondary hyperparathyroidism in patients maintained by hemodialysis. Am J Med 56:827-832, 1974
317. Sherrard DJ: AluminumMuch ado about something. N Engl J Med 324:558-559, 1991
318. Morrissey J, Rothstein M, Mayor G, Slatopolsky E: Suppression of parathyroid hormone secretion by aluminum. Kidney Int 23:699-704, 1983
319. Ott SM, Maloney NA, Coburn JW, Alfrey AC, Sherrard DJ: The prevalence of bone aluminum deposition in renal osteodystrophy and its relation to the response to calcitriol therapy. N Engl J Med 307:709-713, 1982
320. Windus DW, Stokes TJ, Julian BA, Fenves AZ: Fatal Rhizopus infections in hemodialysis patients receiving deferoxamine. Ann Intern Med 107:678-680, 1987
321. Sawyer N, Noonan K, Altmann P, Marsh F, Cunningham J: High-dose calcium carbonate with stepwise reduction in dialysate calcium concentration: Effective phosphate control and aluminium avoidance in haemodialysis patients. Nephrol Dial Transplant 4:105-109, 1989
322. Goldberg DI, Dillon MA, Slatopolsky EA, Garrett B, Gray JR, Marbury T, Weinberg M, Wombolt D, Burke SK: Effect of RenaGel, a non-absorbed, calcium- and aluminium-free phosphate binder, on serum phosphorus, calcium, and intact parathyroid hormone in end-stage renal disease patients. Nephrol Dial Transplant 13:2303-2310, 1998
323. Morrison G, Michelson EL, Brown S, Morganroth J: Mechanism and prevention of cardiac arrhythmias in chronic hemodialysis patients. Kidney Int 17:811-819, 1980
324. Nappi SE, Virtanen VK, Saha HH, Mustonen JT, Pasternack AI: QTc dispersion increases during hemodialysis with low-calcium dialysate. Kidney Int 57:2117-2122, 2000
325. Sprague SM, Moe SM: Clinical manifestations and pathogenesis of dialysis-related amyloidosis. Semin Dial 9:360-369, 1996
326. Zingraff JJ, Noel LH, Bardin T, Atienza C, Zins B, Drueke TB, Kuntz D: Beta 2-microglobulin amyloidosis in chronic renal failure. N Engl J Med 323:1070-1071, 1990
327. Campistol JM, Cases A, Torras A, Soler M, Munoz-Gomez J, Montoliu J, Lopez-Pedret J, Revert L: Visceral involvement of dialysis amyloidosis. Am J Nephrol 7:390-393, 1987
328. Campistol JM, Sole M, Munoz-Gomez J, Lopez-Pedret J, Revert L: Systemic involvement of dialysis-amyloidosis. Am J Nephrol 10:389-396, 1990
329. Gal R, Korzets A, Schwartz A, Rath-Wolfson L, Gafter U: Systemic distribution of beta 2-microglobulin-derived amyloidosis in patients who undergo long-term hemodialysis. Report of seven cases and review of the literature. Arch Pathol Lab Med 118:718-721, 1994
330. Benz RL, Siegfried JW, Teehan BP: Carpal tunnel syndrome in dialysis patients: Comparison between continuous ambulatory peritoneal dialysis and hemodialysis populations. Am J Kidney Dis 11:473-476, 1988
331. Cornelis F, Bardin T, Faller B, Verger C, Allouache M, Raymond P, Rottembourg J, Tourliere D, Benhamou C, Noel LH, et al: Rheumatic syndromes and beta 2-microglobulin amyloidosis in patients receiving long-term peritoneal dialysis. Arthritis Rheum 32:785-788, 1989
332. Moriniere P, Marie A, el Esper N, Fardellone P, Deramond H, Remond A, Sebert JL, Fournier A: Destructive spondyloarthropathy with beta 2-microglobulin amyloid deposits in a uremic patient before chronic hemodialysis. Nephron 59:654-657, 1991
333. Karlsson FA, Groth T, Sege K, Wibell L, Peterson PA: Turnover in humans of beta 2-microglobulin: The constant chain of HLA-antigens.