KDOQI (Kidney Disease Outcomes Quality Initiative)


NKF KDOQI GUIDELINES

KDOQI Clinical Practice Guideline for Nutrition in Children with CKD: 2008 Update


Biographical and Disclosure Information

Bradley A. Warady, MD (Work Group Co-Chair), is Associate Chairman, Department of Pediatrics, Chief of Nephrology and Director of Dialysis and Transplantation at The Children's Mercy Hospital, and Professor of Pediatrics at the University of Missouri–Kansas City School of Medicine. He is a member of the Board of Directors of the NAPRTCS. Dr Warady helped establish the International Pediatric Peritonitis Registry (IPPR) and he currently serves as Co-Principal Investigator of the International Pediatric Peritoneal Dialysis Network (IPPN) and the National Institutes of Health (NIH)-funded Chronic Kidney Disease in Children (CKiD) study. He coedited the books CAPD/CCPD in Children and Pediatric Dialysis and he has published more than 250 articles and book chapters. He is Chairman of the Pediatric Liaison Committee of the International Society of Peritoneal Dialysis and he has been a member of the KDOQI PD Adequacy, Pediatric Nutrition and Pediatric Bone Work Groups for the NKF. Dr Warady also serves as an Associate Editor for Peritoneal Dialysis International and sits on the Editorial Boards of Pediatric Nephrology and the Clinical Journal of the American


Society of Nephrology.
Advisor/Consultant: AMAG Pharmaceuticals, Amgen, Watson
Speaker: Amgen, Genentech, Watson
Grant/Research Support: NIH, Amgen, Baxter

Donna Secker, PhD, RD (Work Group Co-Chair), is an Academic and Clinical Specialist, Department of Clinical Dietetics, Division of Nephrology and The Transplant Centre at The Hospital for Sick Children, Toronto, Canada, and Project Investigator, Clinical Research Centre Research Institute, The Hospital for Sick Children. Dr Secker completed her PhD in Medical Sciences and Masters in Nutritional Sciences at University of Toronto and maintains a research interest in pediatric nutritional assessment and malnutrition in children with CKD. She is a recipient of a CIHR Clinician Scientist Training Program scholarship and is a Fellow of Dietitians of Canada. Dr Secker is a current editorial board member for Journal of Renal Nutrition and has served as a reviewer for numerous journals, including Advances in Chronic Kidney Disease, Journal of Dietetic Practice and Research, Peritoneal Dialysis International, and Journal of Pediatric Research. Dr Secker has also recently contributed book chapters in Nutrition and Kidney Disease and Clinical Pediatric Nephrology.

Dr Secker reported no relevant financial relationships.

Bethany J. Foster, MD, is an Assistant Professor of Pediatrics at McGill University in Montreal, Canada, where she is also an Associate Member of the Department of Epidemiology, Biostatistics and Occupational Health. She holds a Masters degree in Clinical Epidemiology from the University of Pennsylvania. She has studied body composition and nutrition in children with CKD, using a variety of methods. She is a member of the American Society of Nephrology, the Canadian Society of Nephrology, the Canadian Association of Pediatric Nephrologists, the International Society of Nephrology, the American Heart Association, and the American Society for Transplantation.

Dr Foster reported no relevant financial relationships

Stuart Goldstein, MD, is an Associate Professor of Pediatrics at the Baylor College of Medicine in Houston, TX. He is the Medical Director of the Dialysis Unit and Pheresis Service at the Texas Children's Hospital, also in Houston. Dr Goldstein is a member of the American Academy of Pediatrics, the American Society of Nephrology, the International Pediatric Nephrology Association, the American Society of Pediatric Nephrology, the International Society of Nephrology, and the Society for Pediatric Research. In addition, he is Chairman of the Medical Advisory Committee to the FORUM of ESRD Networks and a member of the Medical Review Board for the End-Stage Renal Disease Network of Texas, is the Pediatric Nephrologist Representative for the International Society of Nephrology Commission of Acute Renal Failure, and is on the Clinical Affairs Committee for the American Society of Pediatric Nephrology. Dr Goldstein has investigated the use of IDPN to treat malnourished pediatric patients receiving HD and has assessed the use of nPCR as a marker of nutrition status in pediatric patients receiving HD.

Advisor/Consultant: Dialysis Solutions, Inc; Gambro Renal Products
Grant/Research Support: Baxter; Dialysis Solutions, Inc; Gambro Renal Products

Frederick Kaskel, MD, PhD, is Professor of Pediatrics, Vice Chairman for Affiliate & Network Affairs and Chief, Section on Nephrology, at Children's Hospital at Montefiore. Dr Kaskel is a Distinguished Alumnus of Monmoth College, Monmouth, IL and University of Cincinnati College of Medicine and has completed a nephrology fellowship at Albert Einstein College of Medicine, NY. He is Past President of the American Society of Pediatric Nephrology; Past Chairman of the NKF Council of Pediatric Nephrology and Urology; and also has served as an Advisor to the Food and Drug Administration on the Cardiovascular Renal Advisory Committee. He received numerous honors, including the National Medical Award in Pediatric Nephrology from the Kidney and Urology Foundation of America and a citation in The Best Doctors in America. Dr Kaskel is a principal investigator on the NIH grant Focal Segmental Glomerulosclerosis in Children and Young Adults and President of the Fifteenth Congress of the International Pediatric Nephrology Association to be held in NYC, Aug 29 to Sept 2, 2010. He has also published extensively with more than 100 publications in peer-reviewed journals and various book chapters and monographs.

Grant/Research Support: NIH

Sarah Ledermann, MB, MRCPCH, is an Associate Specialist in Pediatric Nephrology and Honorary Lecturer at Great Ormond Street Hospital (GOSH) for Children NHS Trust in London. Her primary remit for the past 20 years has been to care for infants and children with chronic kidney disease. She established a specialized clinic for this group of patients and has implemented an intensive feeding program resulting in improved growth and outcome, the results of which are internationally recognized. She developed specific protocols in CKD, including management of bone disease, prevention of anemia, immunizations schedules, safe placement of gastrostomies, and treatment of peritonitis and exit-site infections. Some of these now form the basis for recommendations in the Renal Association's Paediatric Standards Document. Dr Ledermann had a major role in the establishment of the infant PD programme at GOSH and during the last 3 years helped to develop a combined low clearance/dialysis clinic for all age groups to facilitate successful renal transplantation. Attention to detail and close collaboration with urologists, radiologists, transplant surgeons, dietitians, social workers, and clinical nurse specialists, as well as clear communication with families and local teams, is vital for high-quality patient care and has been a particular feature of her work.

She has authored several research articles relating to improvements in the management of the child with CKD published in Pediatric Nephrology, The Journal of Pediatrics, and Pediatric Transplantation.

Dr Ledermann reported no relevant financial relationships.

Franz S. Schaefer, MD, is Professor of Pediatrics and Chief of the Pediatric Nephrology division at Heidelberg University Medical Center. Dr Schaefer received his MD at Würzburg University Medical School. He established several important clinical research consortia in pediatric nephrology, such as the Mid European Pediatric Peritoneal Dialysis Study Group (MEPPS), the European Study Group on Progressive Chronic Kidney Disease in Children (ESCAPE), the International Pediatric Peritonitis Registry (IPPR), and the International Pediatric Peritoneal Dialysis Network (IPPN). Dr Schaefer is also a member of the KDIGO Work Group for Acute Kidney Injury and a current council member of the International Pediatric Nephrology Association (IPNA) and the International Society of Peritoneal Dialysis (ISPD). He has published more than 250 articles and book chapters and coedited the books Comprehensive Pediatric Nephrology and Pediatric Dialysis. Dr Schaefer serves as an Assistant Editor for Pediatric Nephrology, Pediatric Section Editor for Nephrology Dialysis Transplantation, and sits on the Editorial Boards of Peritoneal Dialysis International, BioMed Central Nephrology, and Current Pediatric Reviews.

Advisor/Consultant: Amgen, AstraZeneca

Nancy S. Spinozzi, RD, LDN, has been a Renal Dietitian Specialist at Children's Hospital, Boston, MA, since 1974. She completed her undergraduate degree in nutrition at Cornell University and Dietetic Internship at Massachusetts General Hospital. Ms Spinozzi is a current member of the American Dietetic Association and the Council on Renal Nutrition. She has served on several NKF committees, including Patient Services Committee, Early Intervention and Prevention Task Force, and the Family Focus Advisory Group. As a member of the Council on Renal Nutrition, she has served on editorial boards of CRN Quarterly and Journal of Renal Nutrition and as Chairman of Communications Committee, Annual Scientific Program and Nominating Committee. Ms Spinozzi is also a recipient of the NKF of New England Gift of Life Outstanding Nephrology Nutrition Award and NKF Trustees Award and has contributed chapters to numerous texts, including most recently Nutrition in Pediatrics and Manual of Pediatric Nutrition.

Ms Spinozzi reported no relevant financial relationships.

KDOQI Chair

Michael V. Rocco, MD, MSCE, is Professor of Medicine at Wake Forest University in Winston-Salem, NC. He received his MD degree from Vanderbilt University in Nashville, TN, and also served his Internal Medicine residency at Vanderbilt. He completed a nephrology fellowship at the University of Pennsylvania in Philadelphia, PA, and received a master's degree in epidemiology at Wake Forest University. He has been on the faculty of the Wake Forest University School of Medicine since 1991 and currently holds the Vardaman M. Buckalew Jr Chair in Nephrology. He has more than 100 manuscripts and book chapters in the areas of HD, PD, nutrition, chronic renal failure, and epidemiology. He has served as the clinical center Principal Investigator at Wake Forest for several NIH trials, including the HEMO Study, the Acute Renal Failure Trial Network, the Dialysis Access Consortium, and the Frequent Hemodialysis Network. Dr Rocco served as the Vice-Chair for KDOQI from 2003 to 2008 and was Vice-Chair for the NKF-KDOQI Hypertension Work Group. He was also a work group member of the Centers for Medicare & Medicaid Services (CMS) ESRD Clinical Performance Measures Quality Improvement Committee and served as the chair of the PD subcommittee.

Advisor/Consultant: Amgen; DaVita; Mitsubishi-Tanabe; Renaissance Health Care

Methods Consultants

Katrin Uhlig, MD, MS, is the Director, Guideline Development at the Tufts Center for Kidney Disease Guideline Development and Implementation, in Boston, MA; Assistant Professor of Medicine at Tufts University School of Medicine; and a nephrologist at Tufts Medical Center. Dr Uhlig completed training in internal medicine, nephrology, and rheumatology in Germany (Aachen University Hospital and Munich University Hospital) and the United States (Georgetown University Medical Center and Tufts Medical Center). Since 2001, she participates in or directs the evidence review for KDOQI and KDIGO guidelines. In 2005, she co-chaired the KDIGO Evidence Rating Group to develop a consensus on grading of KDIGO guidelines. From 2006 to 2007, she served as Co-Editor of the American Journal of Kidney Diseases. Her focus in teaching and research is in evidence-based medicine, systematic review, CPG development, and critical literature appraisal.

Dr Uhlig reported no relevant financial relationships.

Ethan Balk, MD, MPH, is Director, Evidence-based Medicine at the Tufts Center for Kidney Disease Guideline Development and Implementation, in Boston, MA, and Assistant Professor of Medicine at Tufts University School of Medicine. Dr Balk completed a fellowship in Clinical Care Research. His primary research interests are evidence-based medicine, systematic review, CPG development, and critical literature appraisal.

Dr Balk reported no relevant financial relationships.

 

 

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