KDOQI (Kidney Disease Outcomes Quality Initiative)


NKF KDOQI GUIDELINES

Executive Summaries | Anemia | Hemodialysis | Peritoneal Dialysis |
Vascular Access | Nutrition | CKD 2002 | Dyslipidemias | Bone Metabolism | Hypertension and Antihypertensive Agents | Cardiovascular Disease in Dialysis Patients | History of K/DOQ | Pediatric Bone |

KDOQI Clinical Practice Guidelines for Bone Metabolism and Disease in Children With Chronic Kidney Disease


Biographical Sketches of Work Group Members

Craig B. Langman, MD (Work Group Co-Chair), is the Isaac A. Abt MD Professor of Kidney Disease at the Feinberg School of Medicine at Northwestern University and Head of Kidney Diseases and Director of Dialysis at Children's Memorial Medical Center in Chicago. Dr Langman's research has focused on the anatomical, biochemical and clinical expression of inherited or acquired disorders of calcium, phosphorus and vitamin D metabolism in infants, children, and adolescents. He has pioneered the use of noninvasive testing in children to assess bone cell function. Dr Langman has published more than 160 articles, chapters, and reviews in his discipline and currently serves as the Senior Associate Editor for the American Journal of Nephrology and on the Editorial Board for the Journal for Bone and Mineral Research. He previously served on the Editorial Advisory Board of Pediatric Nephrology, Advances in Chronic Kidney Disease and Pediatric Endocrinology. Dr Langman has served as President of the American Board of Pediatrics sub board of Pediatric Nephrology, the American Society of Pediatric Nephrology, and the Council of American Kidney Societies. He has served on the Scientific Advisory Board, Public Policy, and the Executive Committee of the Council of Pediatric Urology and Nephrology Committees, among others, of the National Kidney Foundation. He has also served on the Growth Advisory Board of the North American Pediatric Renal Transplant Cooperative Study. He serves as a consultant for many pharmaceutical laboratories, health care companies, and health care related Foundations, including Merck USA, Roche Pharmaceuticals, Novartis, Genentech, Amgen, Bone Care International, Abbott Laboratories, and the Oxalosis and Hyperoxaluria Foundation.

Isidro B. Salusky, MD, FAAP (Work Group Co-Chair), is Professor of Pediatrics at UCLA School of Medicine, Program Director of the UCLA General Clinic Research Center, and Director of the Pediatric Dialysis Program. He has a long-standing interest in the fields of growth and nutrition in children with renal failure that has ranged from experimental models to patients treated with maintenance dialysis. Dr Salusky has done extensive work to characterize the syndromes of renal osteodystrophy in children with chronic renal failure undergoing regular dialysis and postrenal transplantation. Dr Salusky has published more than 150 papers and is very active in many professional societies. During the course of these studies, Dr Salusky has been successful in obtaining funding from the National Institutes of Health, as well as from other profit and nonprofit organizations. He is a consultant for Genzyme, Inc., Bone Care International, and Abbott Laboratories.

Larry Greenbaum, MD, PhD, is the Associate Professor of Pediatrics and Vice Chair of the Pediatric IRB at the Medical College of Wisconsin in Milwaukee, WI. He has been a principal investigator for multicenter studies in the areas of pediatric dialysis and transplantation. He co-edited the textbook Practical Strategies in Pediatric Diagnosis and Therapy and has written the “Pathophysiology of Body Fluids and Fluid Therapy” section for the next edition of Nelson Textbook of Pediatrics. His research on nutritional rickets has led to policy changes in the Wisconsin WIC program. He has received multiple teaching awards at the Medical College of Wisconsin and UCLA. He has been a reviewer for numerous journals, including the American Journal of Kidney Disease, Pediatric Nephrology and Peritoneal Dialysis International. He serves on the Medical Advisory Board of the Oxalosis and Hyperoxaluria Foundation and the Medical Advisory Committee of the NKF of Wisconsin.

Harald Jueppner, MD, is the Associate Professor of Pediatrics at Harvard Medical School in Boston, Massachusetts. A researcher interested in areas such as bone and mineral homeostasis, cartilage and bone development and uremic bone disease, Dr Jueppner also serves as Associate Biologist and Associate Pediatrician at the Massachusetts General Hospital in Boston. He has served as an invited guest speaker in numerous international symposiums including the European Renal Association– European Dialysis and Transplantation Association in Geneva, Switzerland and the International Bone Forum in Yokohama, Japan. Dr Jueppner is the author of numerous scientific papers in his field and is the President of Advance in Mineral Metabolism.

Mary Leonard, MD, is the Assistant Professor of Pediatrics and Epidemiology at The Children's Hospital of Philadelphia. She is also a Senior Scholar at Center for Clinical Epidemiology and Biostatistics (CCEB) and serves on the United States Renal Data System Scientific Advisory Committee. Dr Leonard has special research interest in the assessment of bone liberalization in children, glucocorticoid-induced osteoporosis in children, structural effects of renal osteodystrophy during growth, and dialysis outcomes in children. She has received grants for her research in areas such as Structural Effects of Renal Osteodystrophy During Growth and Glucocorticoid-Induced Osteoporosis in Children. She is also an active member of several organizations including the American Society of Pediatric Nephrology, the International Pediatric Nephrology Association and the American Society of Nephrology.

Pauline Nelson, RD, is the Pediatric Renal Dietitian at the UCLA Center for the Health Sciences, working with children in the inpatient and outpatient settings on all modalities of end-stage renal disease (ESRD) care. She has participated in many clinical research studies related to growth and nutrition, especially in the areas of recombinant human growth hormone and peritoneal dialysis. Ms Nelson has written numerous professional and lay papers on various aspects of nutrition in ESRD, with a particular emphasis on practical approaches to the delivery of nutrients. She has been active in the American Dietetic Association and the Council on Renal Nutrition of the National Kidney Foundation on local and national levels.

Anthony Portale, MD, is Professor of Pediatrics, Chief of Pediatric Nephrology, and Director of the Pediatric Dialysis Program at the University of California San Francisco Children's Hospital. Dr Portale's clinical and research focus is inherited and acquired disorders of phosphorus and vitamin D metabolism, renal osteodystrophy, and metabolic bone disease in infants and children. He has done extensive work to characterize the physiologic regulation of phosphorus and vitamin D metabolism in individuals and in experimental models. Dr Portale has published numerous scientific papers and book chapters in his field, and serves on the editorial boards for the Journal of Bone and Mineral Research, the American Journal of Nephrology, and Clinical Pediatric Endocrinology.

Bradley A. Warady, MD, is Chief of Nephrology and Director of Dialysis and Transplantation at The Children's Mercy Hospital, and Professor of Pediatrics at the University of Missouri-Kansas City School of Medicine. Dr Warady's clinical and research focus is end-stage renal disease with particular emphasis on peritoneal dialysis. He established the Pediatric Peritoneal Dialysis Study Consortium, and he is on the executive committee of the North American Pediatric Renal Transplant Cooperative Study (NAPRTCS). He currently directs or co-directs research projects on a number of topics including: growth hormone usage in pediatric dialysis patients; peritoneal dialysis adequacy in children; intravenous iron therapy in pediatric patients receiving hemodialysis, and anemia management in children on dialysis. He co-edited the book CAPD/CCPD in Children and has published more than 180 articles and book chapters. Dr Warady serves on the executive committees of the American Society of Pediatric Nephrology and the Nephrology section of the American Academy of Pediatrics. Dr Warady also serves as an Associate Editor for Peritoneal Dialysis International, an Assistant Editor for Advances in Chronic Kidney Disease, and sits on the Editorial Board for Pediatric Nephrology.