New Grant to Study Bone Disease in Infants with Chronic Kidney Disease

December 22, 2016—New York, NY—The National Kidney Foundation has awarded a new research grant to Abigail Eldridge, RD, a pediatric renal dietitian at Children’s Hospital Colorado, to study bone disease in infants with chronic kidney disease (CKD) and end stage renal disease (ESRD).  There are currently no standardized guidelines for the treatment of bone disease in infants who have kidney disease.  Ms. Eldridge and her colleague, Dr. Jens Goebel, have created guidelines to treat and manage bone disease in infants with CKD and ESRD.  Using current studies and guidelines for the pediatric population to develop an algorithm, Ms. Eldridge plans to trial the algorithm in order to develop best practice guidelines for the treatment of bone disease in this patient population. 

“Infants suffering from chronic kidney disease and end stage renal disease are a small, yet growing, population,” said Ms. Eldridge.  “A lack of research and evidence-based practice guidelines is worrisome as most growth in height occurs during the first two years of life, and bone mineralization is an important part of early development,” she added.  Childhood CKD is associated with alterations in bone and mineral metabolism; these play a role in growth failure and can lead to low bone density, which impact short-term and long-term fracture risk. 

The research being conducted by Ms. Eldridge will be a multi-center study, including participants from across North America.  It will evaluate how nutritional status and a standardized treatment plan impact various bone metabolism biomarkers and measures of growth rate such as weight, length and head circumference percentiles.  This study will also help inform standardization of care and dietary needs of infants with mineral and bone disorder due to kidney disease.                                                                                                 

The two-year grant, totaling $70,000, was made possible through funds provided by a Keryx Renal Nutrition Research Grant.  By supporting those who aspire to study the care of kidney disease patients, National Kidney Foundation and Keryx are making an important investment in the future of the scientific community dedicated to kidney research.  The Keryx Renal Nutrition Research Grant funds a renal dietitian whose research and career goals are directed to evaluating the care of the CKD patient with the associated co-morbidities of iron deficiency anemia (IDA) or chronic kidney disease-mineral bone disorder (CKD-MBD). 

“We are very pleased to partner with Keryx in providing this grant.  Funding cutting-edge research is important to advancing our knowledge of kidney disease, developing new methods to slow its progression and finding innovative ways to improve treatment,” said Kevin Longino, CEO of National Kidney Foundation and a kidney transplant patient. “Supporting researchers, like Ms. Eldridge, who seek to help our youngest patient population makes this grant all the more meaningful,” added Longino. 

Kidney Disease Facts
1 in 3 American adults is at risk for kidney disease.  26 million American adults have kidney disease—and most aren’t aware of it.  Risk factors for kidney disease include diabetes, high blood pressure, family history, and age 60+.  People of African American; Hispanic; Native American; Asian; or Pacific Islander descent are at increased risk for developing the disease.  African Americans are 3 ½ times more likely, and Hispanics 1 ½ times more likely, to experience kidney failure.

The National Kidney Foundation (NKF) is the largest, most comprehensive and longstanding organization dedicated to the awareness, prevention and treatment of kidney diseaseFor more information about the NKF visit www.kidney.org.