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Kidney cancer overview Kidney cancer is a disease that starts in the kidneys. It happens when healthy cells in one or both kidneys grow out of control and form a lump (called a tumor). Kidney cancer signs and symptoms In the early stages, most people don’t have...
Hepatitis C Hepatitis C virus infection (HCV) is associated with increased risk of liver fibrosis or cirrhosis and development of hepatocellular carcinoma.1,2 HCV infection is also a common indication for liver transplant in the United States. The HCV genome is a single-stranded, positive sense RNA...
What is HIV? HIV (human immunodeficiency virus) is a virus that infects and damages your immune system. Your immune system helps your body defend itself against infection and other disease. HIV attacks and destroys the disease-fighting cells of your immune system and leaves your body weak against...
What is Kidney Cancer? - (Available in Spanish) Who is at Risk? - (Available in Spanish) How is Kidney Cancer Found? - (Available In Spanish) Treatments for Kidney Cancer - (Available In Spanish) Talking with Your Healthcare Professional - (...
What is an ectopic kidney? An ectopic kidney is a kidney that is out of place. An ectopic kidney is caused by a birth defect. What causes an ectopic kidney? An ectopic kidney happens while a baby is growing in the womb. Normally, the kidneys form a kidney bud within the pelvis (hip...
People with simple kidney cysts have sacs that are filled with fluid within their kidneys. It is possible to have one or more cysts in one or both kidneys. The exact cause of simple kidney cysts is not known but they tend to be more common as people age. Simple kidney cysts rarely cause problems...
Medullary sponge kidney (MSK) is a congenital disorder, meaning it is present at birth. MSK occurs when small cysts (sacs) form either on tiny tubes within the kidney (known as tubules) or the collecting ducts (a channel where urine is collected for removal). These cysts can reduce the outward flow...
What is anemia? Anemia happens when your red blood cells are in short supply. Red blood cells carry oxygen from your lungs to all parts of your body, giving you the energy you need for your daily activities. What are the symptoms of anemia? Anemia can cause you to: Look pale Feel tired Have little...
Goodpasture's Syndrome is an uncommon autoimmune disease that affects both the kidneys and the lungs. An autoimmune disease means that the immune system, which usually protects the body from infection, attacks healthy parts of the body by mistake. What causes the disease? The body's immune system...
Thin basement membrane disease (TBMD) is an inherited disorder that mainly affects the glomeruli, which are tiny tufts of capillaries (small blood vessels) in the kidneys that filter wastes from the blood. It is a rare disorder that has been diagnosed in less than 1 percent of the population. The...
What is membranous nephropathy? Many diseases can affect your kidney function by attacking and damaging the glomeruli, the tiny filtering units inside your kidney where blood is cleaned. Glomerular diseases include many conditions with many different genetic and environmental causes. Membranous...
What is Fabry Disease? Fabry disease is a rare disorder that happens when the body lacks an important enzyme called alpha-galactosidase A (alpha GAL). This enzyme breaks down certain fats so they can be removed from cells and passed out of the body or be recycled for other functions. When alpha GAL...
Nephrotic syndrome may occur when the filtering units of the kidney are damaged. This damage allows protein normally kept in the plasma to leak into the urine in large amounts, which reduces the amount of protein in your blood. Since the protein in the blood helps keep fluid in the bloodstream,...
What is minimal change disease? Many diseases can affect your kidney function by attacking and damaging the glomeruli, the tiny filtering units inside your kidney where blood is cleaned. The conditions that affect your glomeruli are called glomerular diseases. One of these conditions is minimal...
What is membranoproliferative glomerulonephritis? Many diseases can affect your kidney function by attacking and damaging the glomeruli, the tiny filtering units inside your kidney where blood is cleaned. The conditions that affect your glomeruli are called glomerular diseases. Glomerular diseases...
C3G (complement 3 glomerulopathy) is a rare chronic kidney disease that can have a major impact on a patient's health throughout their life. Recognizing this impact, the National Kidney Foundation has created this website to raise awareness and understanding about C3G. Check back for...
What is a nephrectomy? Nephrectomy (nephro = kidney, ectomy = removal) is the surgical removal of a kidney. The procedure is done to treat kidney cancer as well as other kidney diseases and injuries. Nephrectomy is also done to remove a healthy kidney from a donor (either living or deceased) for...
What is glomerular disease? Your kidneys may be small, but they perform many vital functions that help maintain your overall health, including filtering waste and excess fluids from your blood. Your kidneys have about one million tiny filter units called nephrons. Each nephron has a glomerulus, so...
Complement 3 glomerulopathy (C3G) is a rare kidney disease that has two forms: dense deposit disease (DDD) and C3 glomerulonephritis (C3GN). Each is caused by genetic or acquired problems in controlling the body’s complement system, which helps fight infections. Genetic problems can be inherited or...
What is interstitial cystitis? Interstitial cystitis (IC) is a disorder in which the bladder (the organ that stores urine before it is passed out of the body) is overly sensitive, and usual causes for this, such as infection, cannot be found. The major symptoms are: pain in the pelvic area urgent...