Last updated: October 05, 2026
Medically reviewed by: NKF Patient Education Team
Participating in kidney disease clinical trials helps research new treatments. Find opportunities and ask your healthcare provider about local studies.
About Clinical Trials for Kidney Diseases
Volunteering to participate in clinical trials helps researchers learn more about diseases and finding new ways to treat them. Although there are risks, clinical trial participation can be very rewarding because you can help learn more about today’s diseases while also helping discover treatments that may help people in the future.
Many people with kidney diseases want to know more about how to participate in clinical trials. This directory of trials features opportunities from partners who have requested the National Kidney Foundation to help bring these research opportunities to you. Other opportunities to participate in clinical research exist – ask your healthcare provider about other clinical trials happening in in your area.
Chronic Kidney Disease and High Blood Pressure
AstraZeneca is conducting The BaxDuo Pacific study: The study will assess the safety, tolerability and efficacy of Baxdrostat in Combination with Dapagliflozin Compared with Dapagliflozin Alone on Renal Outcomes and Cardiovascular Mortality in Participants with Chronic Kidney Disease and High Blood Pressure. To find out more go to: The BaxDuo Pacific Study
Chronic Kidney Disease and Metabolic Acidosis
The REVIVE Ph3 study is evaluating veverimer, an investigational oral therapy, in adults with chronic kidney disease (CKD) and metabolic acidosis, a condition that occurs when the kidneys are unable to remove enough acid from the body. Veverimer is designed to bind and remove acid through the digestive tract and increase bicarbonate levels without adding sodium or potassium. The study will evaluate the safety and effectiveness of veverimer compared with placebo in approximately 150 adults with moderate-to-severe CKD and metabolic acidosis. For more information, please visit Clinical Trials.gov
Membranous Nephropathy (MN)
- REBOOT (NIH National Institute of Allergy and Infectious Diseases): The Immune Tolerance Network (ITN) is conducting a primary membranous nephropathy study, sponsored by the National Institute of Allergy and Infectious Diseases (NIAID). For more information or if you are interested in participating in this study, please visit the REBOOT website.
The National Kidney Foundation shares these clinical trial listings to help advance research for kidney diseases. The NKF does not endorse any specific commercial product studied or used in any of these trials. Each trial has different eligibility criteria. For more specific information, visit the website for the trial.
Clinical Trial Databases
In addition to the opportunities listed above, several databases exist to help you find a clinical trial and learn how to get involved. Some examples are provided below. They can be accessed using the following links:
- CenterWatch: Use this listing service to find an industry-sponsored clinical trial that is currently seeking volunteers.
- Clinicaltrials.gov: Search this database of publicly and privately supported clinical studies around the world
- National Heart, Lung, and Blood Institute (NHLBI) Clinical Trials: Search this database of studies for diseases and conditions sponsored by the NHLBI to see if you or a loved one is eligible.
- ResearchMatch.org: Create a volunteer profile for yourself or for someone else as their parent or guardian. This NIH-funded resource is a free, secure registry that will keep you informed of clinical research studies that need volunteers matching your profile.
- Antidote: Let's find cures together. Click start in the box below and answer a series of questions to see if there is a clinical trial that may be a match for you. The link in the box below will open a new browser window or tab so make sure you have enabled pop-ups.
The clinical trial matching tool provided in this portal is intended to offer helpful information about potential clinical research opportunities based on the information that you enter. However, it may not identify all available clinical trials. This tool relies on publicly available databases and may be limited by the completeness or accuracy of those sources. We encourage you to also speak with your healthcare provider and/or visit clinicaltrials.gov or other trusted sources to explore additional opportunities. Participation in a clinical trial is a personal decision that should be made in consultation with your healthcare team.
