Glomerular filtration rate (GFR) is the best overall index of kidney function. Normal GFR varies according to age, sex, and body size, and declines with age. The National Kidney Foundation recommends using the CKD-EPI Creatinine Equation (2009) to estimate GFR.
NKF and the American Society of Nephrology have convened a Task Force to focus on the use of race to estimate GFR. Read more about the task force here.
|CKD-EPI creatinine equation (2009)||mL/min|
|CKD-EPI creatinine-cystatin equation (2012)||mL/min|
|CKD-EPI cystatin C equation (2012)||mL/min|
|MDRD study equation||mL/min|
For persons under 18 years of age, use the pediatric GFR calculator.
Is it CKD?
Either of the following must be present for ≥3 months to be CKD:
- GFR less than 60 ≥3 months
- ACR ≥30 mg/g or other markers of kidney damage
Click to learn more.
Equation used to estimate GFR?
What is the patient’s ACR?†
Based on the information supplied:
|GFR category is:‡||see note below|
|ACR category is:**|
|CKD classification is:|
|Risk of progression is:|
|Frequency of monitoring should be:|
|Referral to a nephrologist is:|
In the absence of evidence of kidney damage, neither GFR category G1 nor G2 fulfill the criteria for CKD.
† Neither the category of GFR nor the category of albuminuria alone can fully capture prognosis of CKD. Persistent and increased albuminuria has been shown to be an independent risk factor for CKD progression.
‡In the absence of evidence of kidney damage, neither GFR category G1 nor G2 fulfill the criteria for CKD.
**ACR 30-300 mg/g for > 3 months indicates CKD.
- CKD-EPI Creatinine Equation (2009)
- CKD-EPI Creatinine-Cystatin Equation (2012)
- CKD-EPI Cystatin C Equation (2012)
- MDRD Study Equation
Learn more about CKD-EPI Collaboration and estimating GFR at www.ckdepi.org.