Last updated: June 09, 2026
Medically reviewed by: NKF Education Team
This patient-facing FAQ helps healthcare professionals explain kidney xenotransplantation in clear, plain language. It can support conversations with patients, families, and care partners who are asking about pig kidney research, clinical trials, possible risks and benefits, and what questions to bring to the transplant team.
Kidney xenotransplantation is still experimental and is not a standard treatment option. This resource is intended to help patients understand what is known, what is still being studied, and how to make informed decisions if they are considering a clinical trial.
Use this FAQ as a patient communication resource before or during transplant discussions. The FAQ includes plain-language definitions, a basic overview of kidney xenotransplantation, considerations for clinical trials, known and unknown risks, potential benefits, and questions patients may want to ask their transplant team.
More Resources
Clinical Trials
Research
- Patients’ Information Needs for Informed Consent to Participate in First-in-Human Pig Kidney Xenotransplant Clinical Trials: A Mixed Methods Study (E. Gordon, et al., 2025)
- A Decision Aid for Patients Considering Participating in a Pig Kidney Xenotransplant Clinical Trial
- Xenotransplantation of a Porcine Kidney for End-Stage Kidney Disease (T. Kawai et al., 2025)
Patient Engagement with Xenotransplantation
- Kidney Xenotransplantation
- FDA: Xenotransplantation
- NKF’s Patient-Focused Meeting with the FDA on Kidney Xenotransplantation, also called an Externally-led Patient focused Drug Development (or EL-PFDD) Meeting (November 2023)
- Hot Topics in Kidney Health: A Patient Podcast by the National Kidney Foundation – Xenotransplantation Episodes:
- “I Had a Xenotransplant.” With Xeno Recipients Towana Looney and Tim Andrews (aired February 10, 2026)
- A Conversation with Xenotransplantation Experts (aired February 25, 2026)
- Xenotransplantation: Updates on Animal-to-Human Transplants (Audio from NKF webinar on Kidney Xenotransplantation, aired July 21, 2024)
- Pig kidneys in humans? Xenotransplantation explained
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For Kidney Health Professionals Who Want to Stay Informed
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