This calculator provides estimated times to when a patient may require renal replacement therapy or when their current glomerular filtration rate (GFR) decreases by 50%. These estimates are based on a panel of variables from a patient's current visit and their visit approximately one year prior. The tool requires general information (age, sex, diagnosis), markers of kidney disease (GFR, proteinuria), blood pressure, blood chemistry panels (albumin, lipids, anemia) and medications (ACEi/ARB therapy). It is intended to aid clinicians in managing kidney disease for pediatric patients.
It should be noted that estimates from this calculator are not absolute or definitive but reflect an estimated time to needing renal replacement therapy. Please interpret the estimated times within the context of the patient's full clinical profile.
This calculator is for use only by nephrologists and other healthcare providers.
Warady BA, Abraham AG, Schwartz GJ, Wong CS, Muñoz A, Betoko A, Mitsnefes M, Kaskel F, Greenbaum LA, Mak RH, Flynn J, Moxey-Mims MM, Furth S. Predictors of rapid progression of glomerular and nonglomerular kidney disease in children and adolescents: the Chronic Kidney Disease in Children (CKiD) Cohort. Am J Kidney Dis 2015; 65:878-888. PMID: 25799137
Adapted from original article for online calculation by Derek K. Ng, PhD and Shuai Jiang, MHS (2019).
Department of Epidemiology
Johns Hopkins Bloomberg School of Public Health
Bradley A. Warady, MD and Kathleen Mallett, APRN, FNP-C, CNN-NP for guidance and insight.
Children's Mercy Hospital
Kansas City, MO
Bradley A. Warady, M.D. The McLaughlin Family Endowed Chair in Nephrology
Director, Division of Pediatric Nephrology
Director, Dialysis and Transplantation
Children’s Mercy Kansas City
Professor of Pediatrics
UMKC School of Medicine
Derek Ng, MD Johns Hopkins Bloomberg School of Public Health
Shuai Jiang, MHS PhD Candidate, Quantitative Biomedical Sciences
Dartmouth Geisel School of Medicine
Hanover, New Hampshire