The KFRE are math equations that can predict how high or low your chance (risk) is for reaching kidney failure within the next 2-year and 5-year points in time. Results are given as a percent (%) on a scale of less than 1% to 99.99%. For example, a result of 1% chance of reaching kidney failure within 2 years, with a 5% chance at 5 years, is considered low.
The KFRE use specific information about you and your health called variables. Some variables such as age and gender can't be changed, so they're called non-modifiable variables.
However, other variables such as phosphorus and urine albumin-to-creatinine ratio (UACR) can be improved to lower your chances of reaching kidney failure, or to prolong the time it takes to reach kidney failure. These variables are modifiable because they can improve with the right care.
By studying the health information of more than 700,000 patients with chronic kidney disease (CKD) in 30 countries around the world, experts found which variables increase a person's chances for reaching kidney failure. These variables are listed below. By clicking a variable, you'll be taken to a page with more information about how it fits into the KFRE and how it might be improved to lower your chances of reaching kidney failure, or at least prolong the time it takes to reach kidney failure.
There are 2 KFRE. The 4 variable equation uses the first four variables only, and the 8 variable equation uses all eight. Your doctor and healthcare team use only your personal variables to calculate your individual risk for kidney failure using one of these equations.